The shared risk of apolipoprotein E ɛ4-allele on hippocampal volume across the spectrum of Alzheimer’s disease and dementia with Lewy bodies: Evidence from the Sunnybrook Dementia Study
Objective: To identify the association of apolipoprotein E ɛ4-allele (APOE-ε4) with hippocampal volumes across the spectrum of Alzheimer’s disease (AD) and dementia with Lewy bodies…Neuromelanin Imaging and Midbrain Volumetry in Progressive Supranuclear Palsy and Parkinson’s Disease
Objective: Using neuromelanin-sensitive magnetic resonance imaging (NM-MRI) and midbrain volumetry, we analyzed differences and relationships between nigral degeneration and midbrain atrophy in PSP and PD…Neuromelanin-MRI in REM sleep behaviour disorder predicts dopaminergic dysfunction and clinical risk of Parkinson’s disease
Objective: To determine whether neuromelanin-MRI signal changes in the substantia nigra and locus coeruleus in patients with REM sleep behaviour disorder (RBD) are predictive of…Patterns of dopamine transporter imaging in subtypes of Multiple System Atrophy
Objective: To investigate the differences in the pattern of striatal (caudate and putamen) dopamine transporter(DAT) loss in a multiple system atrophy (MSA) cohort, based on…Insular atrophy as a marker of depression in Multiple System Atrophy: A voxel-based morphometry study
Objective: The aim of this study was to determine the structural correlates of depressive symptoms in MSA patients. Background: Depression is highly prevalent among patients…Lewy body disease with visual hallucination: Optic radiation abnormalities on phase difference-enhanced imaging (PADRE)
Objective: We assessed structural abnormalities of optic radiation (OR) in healthy subjects (HS) and dementia with lewy body (DLB) patients (with visual hallucination) (VH) on…Diencephalic mesencephalic junction abnormalities in adult-onset movement disorders
Objective: To describe two cases of adult-onset movement disorders with diencephalic-mesencephalic junction dysplasia(DMJD). Background: DMJD is a rare malformation characterized by a poorly defined junction…Multimodal MRI markers modifications in multiple system atrophy: A longitudinal study
Objective: Using multimodal MRI, the aim of the study was to evaluate brain changes due to disease progression in multiple system atrophy (MSA) patients. Background:…Safinamide inhibition of in vivo glutamate release in a rat model of Parkinson’s Disease
Objective: To evaluate whether safinamide inhibits in vivo glutamate (Glu) release in a rodent model of Parkinson’s disease (PD), i.e. the 6-hydroxydopamine (6-OHDA) hemilesioned rat.…Abrogation of Rotenone Induced Behavior, Biochemical and Mitochondrial Deficits in Mice by Curcumin and Ginkgo Biloba: New Combinational Therapy Approach for Parkinson’s Disease
Objective: This study was designed with the objective to find out the possible synergistic effect of Curcumin (Cur) and Methanolic extract of Ginkgo biloba (EGB)…
