Safety and Tolerability of opicapone in Parkinson’s disease
Objective: To evaluate safety and tolerability of opicapone as an add‐on treatment to levodopa in Parkinson's disease (PD) patients. Background: Opicapone is a recently approved…Effect of a Combined Treatment with Botulinum Toxin and Biofeedback Exercises in Pisa Syndrome
Objective: To assess the efficacy of a combined botulinum neurotoxin (BoNT) treatment with biofeedback exercises in a single Parkinson Disease (PD) patient with Pisa Syndrome…The role of mitochondria in modifying penetrance of Parkin gene variants
Objective: To understand whether mitochondrial DNA (mtDNA) mutation load can modify the penetrance of variants in the Parkinson’s disease (PD) causing gene PRKN (Parkin), in…Carotid Intima-Media Thickness and its correlates in people with Parkinson’s disease: a pilot study
Objective: To determine the clinical correlates of carotid intima media thickess in patients with idiopathic Parkinson’s disease (PD). Background: Subclinical cardiovascular disease has been suggested…Circumstances of Falls in Single and Recurrent Fallers with Parkinson’s Disease
Objective: To compare the circumstances of falls among single fallers (1 fall over one year) and recurrent fallers (≥2 falls over one year) with Parkinson´s…To compare early / late onset MSA from the PAN American MSA (PANMSA) database
Objective: Compare two different cohorts of patients with the same pathology differentiated by age of onset. Background: Multiple system atrophy (MSA) is a rare neurodegenerative…Demographic Influences on Wearing Off Symptoms in Parkinson’s Disease
Objective: To examine differences in wearing off symptoms in Parkinson’s Disease (PD) according to gender, age, and age at PD diagnosis. Background: Off symptoms in…Identifying Incident Cases of Neurodegenerative Parkinsonism in a Large Observational At-Risk Cohort: the PPMI study
Objective: To examine the potential of a data-driven approach to identify incident cases of neurodegenerative parkinsonian disorders (PD) in a large observational cohort of individuals…Contribution of pedunculopontine nucleus cholinergic neurons to L-DOPA-induced dyskinesia and PD motor deficits in hemi-parkinsonian rats
Objective: To determine if chemogenetic and pharmacological modulation of pedunculopontine nucleus (PPN) cholinergic neurons can alter L-DOPA-induced dyskinesia and gait deficits in hemi-parkinsonian rats. Background:…Deep Brain Stimulation for atypical tremors secondary to Neuroferritinopathy: Single center experience
Objective: To describe the clinical response to deep brain stimulation. Background: Neuroferritinopathy is a neurodegenerative disease in which mutations in the ferritin light polypeptide (FTL)…
