The role of Parkinson’s disease-associated RHOT1/Miro1 variants in mitochondrial dysfunction and impaired cellular quality control
Objective: In the present study we intent to investigate the effect of mutant Miro1 proteins on mitochondrial function and cellular quality control mechanisms in iPSC-derived…Non-motor symptoms contribute to the caregiver burden in Progressive Supranuclear Palsy
Objective: To investigate the clinical features of NMS in PSP patients and analyze the influences on the burden of the caregivers. Background: NMS was wildly…CHCHD2 maintains the MICOS and inhibits PINK1/Parkin mediated mitophagy in an experimental model of Parkinson’s disease
Objective: To illustrate the mechanism of CHCHD2 in regulating MICOS and mitophagy in Parkinson's disease.To illustrate the mechanism of CHCHD2 in regulating MICOS and mitophagy…Characteristics of gait and quality of life in Parkinson’s disease
Objective: To find the independent correlation between characteristics of gait and QoL in PD, comprehensive assessment of clinical characteristics and objective gait analyses were done…PRKN Positive Parkinson’s Disease Masked as Dopa-Responsive Dystonia
Objective: To report a Parkinson’s disease (PD) patient with PRKN mutation initially diagnosed with dopa-responsive dystonia (DRD), unmasked after developing signs of parkinsonian disease progression.…Genomic variants associated with cognitive impairment in Parkinson’s disease: Ethnicity-specific GWAS
Objective: We aimed to identify the genomic variants that are associated with cognitive impairment in patients with Parkinson’s disease (PD). Background: Cognitive impairment is an…Gender differences of fatigue characteristics in people with Parkinson’s disease
Objective: To investigate gender differences in fatigue characteristics in people with Parkinson’s disease. Background: Fatigue is a common problem among people with Parkinson’s disease. It…Rapid Picture Naming in Parkinson’s Disease Using the Mobile Universal Lexicon Evaluation System (MULES) Test
Objective: To introduce the Mobile Universal Lexicon Evaluation System (MULES) to the visual assessment of patients with Parkinson’s Disease (PD). Background: The MULES is a…The SUNRISE-PD Study, a clinical trial of AXO-LENTI-PD: a CNS-directed gene therapy for the treatment of Parkinson’s Disease
Objective: This presentation will provide an overview of the design and key objectives of the SUNRISE-PD study. Background: Parkinson’s disease (PD) is caused in part,…Quantitative straight and circular walking parameters for detecting ON and OFF medication states in early PD
Objective: To determine gait parameters that differentiate between ON and OFF medication states using mobile health technology (one device at the lower back) in a…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.