Exploratory Quantitative Gait Analysis for Differentiating Parkinson’s Disease from Atypical Parkinsonian Syndromes
Objective: To compare quantitative spatiotemporal and plantar pressure gait parameters between patients with Parkinson’s disease (PD) and atypical parkinsonian syndromes (APS) using instrumented gait analysis.…Investigating the Role of Biallelic EPG5 Variants in Parkinson’s Disease
Objective: Investigate EPG5 role in PD aetiology. Background: Disruption of the lysosome-autophagy pathway is a recurrent feature in Parkinson’s disease (PD). EPG5 bi-allelic loss-of-function variants have been…From Clinical Patterns to Symptom-specific Functional Networks in Dyskinetic Cerebral Palsy
Objective: Investigate clinical motor patterns and evaluate symptom-specific functional motor networks in dyskinetic cerebral palsy. Background: Dyskinetic cerebral palsy (DCP) is a complex movement disorder…Parkinson’s Disease and Osteoporosis Comorbidity: A Bibliometric Analysis and Exploration of Mechanistic Pathways and Key Genes
Objective: Explore the association between Parkinson’s disease (PD) and osteoporosis (OP). Background: In recent years, PD and OP have emerged as significant global public health burdens[1,…Clinical Utility of DaT-SPECT as a Predictive Tool for the Development of Parkinson’s Disease and Related ɑ-synucleinopathies in REM-Behavior Disorder
Objective: The aim of this systematic review was to analyze the available literature and evaluate the efficacy of DaT-SPECT for the prediction of PD phenoconversion…Cross-Family Analysis of Rare Deleterious Variants Segregating in Families with Parkinson’s Disease
Objective: To identify potential novel variants and genes associated with Parkinson’s disease (PD) in multiplex families. Background: Identifying novel genes associated with PD is critical…REM Sleep Behaviour Disorder (RBD) and its relation to Non-motor Symptoms in Progressive Supranuclear Palsy(PSP).
Objective: To examine the frequency of RBD in PSP and its associations with other non-motor symptoms. Background: RBD once considered rare in PSP, is now…The enteric footprint of de novo parkinson’s disease cohort: constipation, inflammation, and nulisa biomarker profiling.
Objective: This study aimed to analyze constipation symptoms and blood, CSF and fecal biomarkers, including a High-plex Profiling of Inflammatory Proteins (NULISA) in a de novo PD cohort. Background: Parkinson’s disease…Stellate Ganglion Block for Restless Legs Syndrome in a Patient with Renal Failure a Case Report
Objective: To report a case of refractory restless legs syndrome (RLS) in a hemodialysis patient with renal failure who achieved significant symptom and sleep improvement…A Retrospective Comparison of Multiple Approaches to LFP-guided and Imaging Guided Contact Selection in Subthalamic Deep Brain Stimulation for Parkinson’s Disease
Objective: To retrospectively compare several local field potential (LFP)-guided approaches for contact selection with an imaging-guided strategy and monopolar reviews, using long-term motor outcome as…
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