From Clinical Patterns to Symptom-specific Functional Networks in Dyskinetic Cerebral Palsy
Objective: Investigate clinical motor patterns and evaluate symptom-specific functional motor networks in dyskinetic cerebral palsy. Background: Dyskinetic cerebral palsy (DCP) is a complex movement disorder…Perceptions and knowledge about Parkinson’s disease fluctuations among patients and caregivers: insights from a qualitative focus group
Objective: To explore the knowledge, perceptions and experiences of people with Parkinson’s disease and caregivers regarding motor and non-motor fluctuations, identifying informational gaps and training…Association of the GCH1 p.Ser80Asn variant with Parkinson’s disease in East Asian populations
Objective: To investigate the clinical relevance and PD risk associated with the GCH1 p.Ser80Asn variant. Background: Heterozygous variants in GCH1 are the most frequent cause…Amyloid PET–Guided Anti-amyloid Therapy in Corticobasal Syndrome Associated with Clinical Improvement
Objective: To clarify the clinical significance of amyloid positron emission tomography (PET) in patients presenting with corticobasal syndrome (CBS) and to describe the potential therapeutic…Clinical and Genetic Profile of the ACTIVATE Population: A Phase 2 Trial of BIA 28-6156 in GBA-PD
Objective: To characterize the patient population enrolled in the ACTIVATE study, a Phase 2 multicenter, randomized, double-blind, placebo-controlled trial assessing the efficacy, safety, tolerability, pharmacodynamics,…Investigating Substantia Nigra Microstructural Integrity as a Potential Predictive Biomarker for Fall Burden in Parkinson’s Disease
Objective: Determine whether baseline Diffusion Tensor Imaging (DTI) measures of the substantia nigra (SN) predict fall incidence and burden in Parkinson’s disease (PD). Background: Degeneration of dopaminergic…Re-evaluating Olfactory Testing and Cardiac 123I-MIBG Scintigraphy in the MDS Clinical Diagnostic Criteria for Parkinson’s Disease
Objective: To determine whether routine implementation of cardiac 123I-MIBG scintigraphy improves the diagnostic performance of the Movement Disorder Society (MDS) “clinically probable Parkinson’s disease (PD)”…A Cerner-based Electronic Prescribing and Medicines Administration (EPMA) Parkinson’s Medicines Care Plan Reduces Time-Critical Medication (TCM) Errors.
Objective: To audit inpatient Parkinson's medication management and implement an EPMA care plan to improve reliability of time-critical prescribing. Background: Parkinson’s UK consistently report that…Automated Identification of Freezing of Gait in Parkinson’s Disease Using Q-Learning Analysis during Virtual Reality–Based Gait Task
Objective: To investigate whether a virtual reality (VR)-based gait task can induce freezing of gait (FOG) in Parkinson’s disease (PD) and whether gait trajectory data…Built Environment and Accessibility to Parkinson’s Disease Community Programs: A Preliminary Analysis
Objective: To examine how the built environment influences accessibility of Parkinson’s disease (PD) programs offered by community-based organizations (CBOs). Background: CBOs offer programs to help…
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