Multimodal Quantitative MRI Improves Parkinson’s Disease Classification
Objective: To evaluate multimodal MRI discrimination of Parkinson’s disease using RPCA–kNN and associations with MDS-UPDRS. Background: Parkinson’s disease (PD) involves progressive neurodegeneration affecting basal ganglia…Neuroimaging-guided automated optimization of deep brain stimulation in Parkinson’s disease: preliminary results
Objective: To evaluate the clinical impact of an automated neuroimaging-guided optimization algorithm (Illumina™, Boston Scientific) for programming in patients with suboptimal response to subthalamic nucleus…Investigating Smiling Asymmetries in Parkinson’s Disease through the Whistle–Smile Reflex
Objective: To assess the frequency, intensity, and asymmetry of smiling elicited by the whistle–smile reflex (WSR) in Parkinson’s disease (PD) compared with healthy controls (HCs),…Amyloid PET–Guided Anti-amyloid Therapy in Corticobasal Syndrome Associated with Clinical Improvement
Objective: To clarify the clinical significance of amyloid positron emission tomography (PET) in patients presenting with corticobasal syndrome (CBS) and to describe the potential therapeutic…Increased Pre-Alpha EEG Functional Connectivity Forecasts Future Cognitive Decline in Parkinson’s Disease
Objective: To evaluate whether resting-state EEG functional connectivity (rsEEG-FC) forecasts cognitive decline three years later in Parkinson’s disease (PD). Background: Cognitive performance and trajectories of…The Anxiolytic Effect of Cannabidiol and Tetrahydrocannabinol in a Reserpine Model of Parkinson’s Disease in Mice
Objective: This study evaluated the anxiolytic effects of CBD, THC, and their combination in a reserpine-induced Parkinson’s mouse model using the Elevated Plus Maze (EPM)…FDG-PET-Based Machine Learning Differentiates Parkinson’s Disease from Other Neurodegenerative Disorders
Objective: To evaluate whether a fluorodeoxyglucose positron emission tomography (FDG-PET) machine learning (ML) framework can be extended to differentiate Parkinson's disease (PD) from other neurodegenerative…Basal Ganglia Hypointensity Associated with Glucose Transporter Type 1 Deficiency Syndrome (GLUT1-DS)
Objective: To present a new case of glucose transporter type 1 deficiency syndrome (GLUT1-DS) diagnosed in adulthood and to describe the associated radiological findings. Background:…Central Nervous System Lesioning Procedures For Dystonia In The Deep Brain Stimulation Era: A Systematic Review
Objective: To evaluate the contemporary clinical role of central nervous system (CNS) lesioning procedures for dystonia in the deep brain stimulation (DBS) era, when DBS…Elevated Myeloperoxidase Levels and Activity as Potential Biomarkers for Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the utility of the myeloperoxidase enzyme level as a diagnostic biomarker in Parkinson’s disease. Background: Myeloperoxidase (MPO) contributes to Parkinson’s disease (PD)…
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