Rotenone induces astrocyte-mediated non-cell autonomous dopaminergic neurotoxicity
Objective: In this study, we examined involvement of astrocytes in rotenone-induced dopaminergic neurotoxicity using primary cultured cells. Background: Several studies reported that pesticide exposure, such…Neuroprotective effects of antidepressant mirtazapine against dopaminergic neurodegeneration in cultured cells and in parkinsonian mice possibly by targeting astrocytes
Objective: In this study, we examined neuroprotective effects of mirtazapine and involvement of astrocytes in the effects using primary cultured cells and parkinsonian mice. Background:…Study of neuroprotective effects of Ginsenside Rg3 , the prototypal epigenetic Sirtuin-1 activator, in targeting microglia activation and neurotrophic factor (NF) neural plasticity in MPTP model of Parkinson’s disease (PD)
Objective: 1) to examine whether the phyto-neurosteroid: Ginsenoside Rg3 recently demonstrated to activate the epigenetic SIRTI signaling, will rescue the motor impairment in rodent model…Curcumin I prevents the developmental defective sensorimotor patterns resulted from Lead poisoning in rat
Objective: In the present investigation, we evaluated the effect of prenatal exposure of rats to lead from neonatal to adult age on the sensorimotor performances…Is there a significant relationship between weight loss and prevalence of side effects of Parkinsonian medication? A retrospective, single-centre analysis, South Wales, UK.
Objective: To investigate if there is a significant relationship between weight loss in persons with Parkinson’s disease and side-effect incidence, and if so to what…Curcumin I protect against copper induced neurobehavioral features of Parkinson’s disease in rat
Objective: evaluate the impact of acute Cu intoxication (10 mg/kg B.W. i.p) for 3 days on the dopaminergic system and locomotor performance, together with the…Brainstem reflexes in patients with neuroleptic-induced akathisia
Objective: We aimed to investigate brainstem reflexes in patients with akathisia. Background: Akathisia is characterized by urge, inner restlessness and constant movement of predominantly lower…Blink reflex recovery cycle to differentiate Progressive Supranuclear Palsy from Corticobasal Degeneration
Objective: To evaluate R2 Blink Reflex Recovery Cycle (BRRC) in patients with Progressive Supranuclear Palsy (PSP) and CorticoBasal Degeneration (CBD) and to determine its diagnostic…Impaired cerebellum to motor cortex associative plasticity in patients with spinocerebellar ataxia type 3
Objective: This study aims to investigate the associative plasticity induced by cerebellum to primary motor cortex (CB-->M1) corticocortical paired associative stimulation (PAS) in patients with…Cortical excitability during a movement compared with postural control task in healthy subjects
Objective: To investigate cortical excitability and surround cortical inhibition during movement compared with postural control task in healthy subjects. Background: Motor control has traditionally been…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.