Rethinking the Divide: Are Cervical Dystonia and Myofascial Pain Two Sides of the Same Coin?
Objective: To compare cervical dystonia (CD) and cervical myofascial pain syndrome (cMPS) and evaluate whether these conditions represent distinct disorders or points along a shared…Unravelling the neural correlates of visual cueing in Parkinson’s disease
Objective: Visual cueing can compensate for impaired automatic gait control in Parkinson's disease (PD) patients experiencing Freezing of Gait (FOG) by engaging goal-directed motor behaviour1.…Type 1 Diabetes and Risk of Parkinson’s Disease: A Nationwide Nested Case–Control Study
Objective: We investigated whether clinically established T1DM is associated with incident PD in a nationwide real-world population. Background: Recent Mendelian randomization studies have suggested a…Fear Across the Disease Course: How Age, Sex, and Disease Duration Influence Different Types of Fear in Parkinson’s Disease
Objective: 1. To determine the prevalence of different fear types in people with Parkinson’s disease (PwP) and their perceived impact on daily activities. 2. To…GBA1 L444P mutation increases susceptibility to neuroinflammation and promotes pro-inflammatory immune responses
Objective: To determine whether the GBA1 L444P mutation increases susceptibility to neuroinflammation and alters immune responses during CNS inflammatory challenge. Background: Mutations in GBA1, which…Genetic Architecture of Essential Tremor: Clinical Misdiagnosis and Structural Variant Contributions to Neurobiological Pathways
Objective: To determine the proportion of other neurological disorders mimicking essential tremor (ET) and investigate the contribution of structural variants (SVs) to ET pathogenesis. Background:…Cholinergic Pathway Degeneration Predicts Differential Phenoconversion to Synucleinopathies in Idiopathic REM Sleep Behavior Disorder
Objective: This cross-sectional and longitudinal study aimed to elucidate the pattern of cholinergic white matter pathway degeneration underlying the phenoconversion trajectories in iRBD patients. Background:…Serum Based biomarkers in Parkinson’s disease with and without cognitive deficits.
Objective: To examine levels of putative biomarker proteins viz., neuronal pentraxin receptor (NPTXR), carnosine dipeptidase-1 (CNDP1), dickkopf-3 (DKK3) in the serum of Parkinson’s Disease patients…Auricular Symptoms in Cervical Dystonia: A Case Series
Objective: To describe 3 cases of cervical dystonia with ear symptoms Background: Dystonia is a movement disorder defined by sustained, patterned, sometimes tremulous postures with…External Validation of a Machine Learning Classifier for Motor Progression in Parkinson’s Disease
Objective: To externally validate a previously published machine learning (ML) classifier for predicting motor symptom progression in Parkinson’s disease (PD) using an independent clinical dataset.…
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