Late Diagnosed Kufor Rakeb Syndrome Presenting as Drug Induced Parkinsonism
Objective: Kufor-Rakeb syndrome (KRS) may present with a wide variety of psychiatric symptoms. This case describes the development of parkinsonism after antipsychotic treatment and the…Resting-state pupil fluctuations reflect monoaminergic brainstem dysfunction associated with non-motor symptoms in early Parkinson’s disease
Objective: To determine whether resting-state pupil fluctuations reflect structural and functional impairment of monoaminergic brainstem nuclei and are associated with non-motor symptom burden in early…Clinical and Cognitive Profile in Patients with Atypical Parkinsonian Syndromes: A Longitudinal Study from a Tertiary Care Center
Objective: To characterize the clinical profile, cognitive performance, sleep and psychiatric features among patients with atypical parkinsonism. Background: Atypical Parkinson syndromes (APS) are group of…Sex Differences in Vascular Burden, Neurodegeneration, and Clinical Progression in Progressive Supranuclear Palsy Richardson Syndrome
Objective: To examine sex differences in cardiovascular risk, white matter hyperintensities (WMH), and neurodegeneration, and to determine their relationship with clinical progression in progressive supranuclear…Severity of Psychotic Symptoms Is Independently Associated with Caregiver Burden in Parkinson’s Disease: A Cross-Sectional Analysis
Objective: To evaluate the association between psychotic symptom severity and caregiver burden in patients with PD. Background: Psychotic symptoms are common in Parkinson’s disease (PD)…Immigration status and Parkinson’s disease: a retrospective matched cohort study
Objective: To investigate whether immigrant status in Parkinson's disease (PD) may be associated with differences in clinical presentation, disease severity, and healthcare engagement. Background: PD…Multidisciplinary Day-Clinic Treatment for Functional Movement Disorders Embedded in a Movement Disorders Center
Objective: To evaluate the feasibility and effectiveness of a multimodal day-clinic treatment program for patients with functional movement disorders (FMD) integrated into a neurological movement…Arm Swing and Early Gait Characteristics in Parkinson’s Disease
Objective: This study aims to develop algorithms that quantify gait parameters reflecting early clinical gait changes in PD. Background: Parkinson’s disease (PD) is the fastest growing neurological…Rest Tremor does Not Predict Response to Focused Ultrasound Thalamotomy in Essential Tremor and Dystonic Tremor
Objective: To investigate whether pre-treatment rest tremor severity predicts outcomes in a cohort of patients with essential tremor/essential tremor plus (ET/ET+) and dystonic tremor (DT).…PDGFB Mutations may Induce Primary Brain Calcification via the Gain-of-Function Mechanism
Objective: This study aims to investigate the expression level of reported PDGFB mutations in human cerebral microvascular endothelial cells (hCMEC/D3), and further propose a potential…
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