Substantia Nigra Echogenicity Associated with Clinical Subtypes of Parkinson’s Disease
Objective: We classified Parkinson’s disease (PD) patients into different subtypes and evaluated the correlation between the substantia nigra (SN) echogenicity and disease progression. Background: It…Automated Differential Diagnosis of Parkinsonian Syndromes Using FDG-PET Metabolic Brain Network Analysis
Objective: To discriminate among parkinsonian patients using an automated network analysis of FDG-PET brain images. Background: Clinical differentiating among parkinsonian syndromes: Parkinson’s disease (PD), multiple…DAT-imaging and clinical phenotypes of Parkinson’s disease
Objective: To evaluate the relationship of motor and nonmotor symptoms with striatal dopaminergic denervation in a cohort of symptomatic PD patients with positive DAT-imaging Background:…α4β2-nicotinic receptor availability in Parkinson’s disease MCI and healthy controls: A pilot imaging study using [18F]-XTRA PET
Objective: We aimed to show that a radiotracer with high affinity to cortical and hippocampal α4β2-nicotinic cholinergic receptors (1) would be reduced in regions associated…Olfactory dysfunction, sleep disturbances, neuronal loss, and regional brain atrophy in an inducible mouse model of Alpha-Synucleinopathy
Objective: The objective of this work is to develop a unique mouse model of spreading α-synucleinopathy to accelerate the development of novel disease-modifying treatments for…Altered connectivity in ventral and dorsal attentional networks in patients with Parkinson’s disease: Association with freezing of gait
Objective: To examine the changes in connectivity of the attentional networks in Parkinson's disease (PD) and their role in freezing of gait (FOG). Background: Deficits…Bupropion causing misdiagnosis in brain dopamine transporter imaging for parkinsonism
Objective: To report long-lasting effects of bupropion on brain dopamine transporter (DAT) binding in a patient with depression and parkinsonism. Background: Striatal DAT imaging is…Association between peripheral inflammation and DATSCAN data of the striatal nuclei in different motor subtypes of Parkinson Disease
Objective: This work was designed to investigate peripheral inflammation in terms of Neutrophil-Lymphocyte ratio (NLR) concerning loss of dopaminergic uptake in caudate and putamen on…Clinical and functional network features of visuoperceptual disturbances in Parkinson’s disease
Objective: To clarify the relationship between functional connectivity changes in the brain and visuoperceptual disturbances in patients with Parkinson's disease (PD). Background: Patients with PD…Compensatory functional activations in early-stage Parkinson’s disease: a cross-sectional motor planning fMRI study
Objective: To assess the dynamic brain responses during planning motor fMRI task in an early-stage cohort of Parkinson’s disease patients. Background: Parkinson’s disease (PD) is…
