Classifying carriers of the G2019S mutation in the LRRK2 gene using MRI radiomics analysis
Objective: To use radiomics approach based on conventional MRI to classify carriers of LRRK2 mutation among non-manifesting first degree relatives of patients with PD. Background:…Return to automaticity: cortical activity during gait in Parkinson’s disease
Objective: This study investigated pre-frontal cortex (PFC) activation while walking in older adults and people with Parkinson’s disease (PD). We specifically examined 1) PFC activation…Early cortical signature of development of visual hallucinations in ‘de novo’ Parkinson’s disease
Objective: To explore, in patients with newly diagnosed Parkinson's disease (PD), grey matter volume (GMV) differences at baseline in those participants who will develop hallucinations…Combined Neurite Orientation Dispersion and Density Imaging and Myelin Imaging Provide New Insights to White Matter Changes of the Neurocognitive-psychiatric Disorder in Parkinson’s Disease
Objective: To identify white matter (WM) changes in PD with neurocognitive-psychiatric symptoms (NPS) using neurite orientation dispersion and density imaging (NODDI) and magnetization transfer saturation…Beta burst coupling across the motor circuit in patients with Parkinson’s disease
Objective: Here, we test the hypothesis that beta bursts not only involve dynamically elevated local synchronisation but also distributed coupling across circuit nodes, further restricting…Microstructural Abnormalities in Drug-naïve Parkinson’s Disease with Mild Cognitive Impairment: A Diffusion Tensor Imaging Study
Objective: The aim of this study was to use MR diffusion tensor imaging to investigate the brain microstructural alterations in newly diagnosed drug-naïve Parkinson’s disease…Clinical and imaging progression in the PARS cohort: Results from 6 years of observation
Objective: The goal of the Parkinson Associated Risk Syndrome (PARS) study is to explore the clinical and biomarker trajectory of individuals in the pre-motor phase…In vivo staging of pathology in REM sleep behaviour disorder
Objective: To study the level of dysfunction in the peripheral and central nervous system in idiopathic REM sleep behaviour disorder (iRBD) patients. Background: α-synuclein (α-syn)…Absence of the nigrosome-1 area in 3 tesla resonance and its relation with hyperechogenicity of the substantia nigra in patients with Parkinson’s disease
Objective: To compare the usefulness of two neuroimaging methods (3TMR and MEcho) to assist in the diagnosis of PD. Background: In patients with Parkinson's disease…Cholinergic basal forebrain and hippocampal structure influence visuospatial function in Parkinson’s disease
Objective: To assess relationships between the structural status of the cholinergic basal forebrain (cBF), hippocampus (HPC) and multi-domain cognitive function in Parkinson’s disease (PD). Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.