Preclinical cardiovascular sympathoexcitatory effects of TD-9855, a novel norepinephrine transporter (NET) inhibitor in development for the treatment of symptomatic neurogenic orthostatic hypotension (nOH) in patients with primary autonomic failure
Objective: TD-9855 is a novel NET inhibitor (1) being studied for the treatment of symptomatic nOH. The objective of the present study was to characterize…Lottery choice task as a detect tool for PD patients with pathological gambling
Objective: We aim to develop a tool lack of stigma to detect patients' impulse control problems. Background: Dopaminergic medication is current major treatment for Parkinson's…Preliminary Study of Depression in Parkinson’s Disease with Diffusion Tensor Imaging
Objective: To explore the relationship between cognitive impairment in Parkinson’s Disease(PD) and the microstructure changes of brain region of interest(ROI) in diffusion tensor imaging(DTI). Background:…Clinical heterogeneity of excessive daytime sleepiness in Parkinson’s disease
Objective: To examine reasons and associated clinical features of excessive daytime sleepiness (EDS) in patients with Parkinson’s disease (PD). Background: Patients with EDS can divided…Non-motor symptoms of Parkinson’s disease: Evaluation of urinary disorders
Objective: Violation of urination, as a manifestation of autonomic failure is common to many patients with Parkinson's disease (PD) and is a very actual. Background:…Degeneration of vagus nerve but not of accessory and phrenic nerve in Parkinson’s disease revealed by high-resolution ultrasound
Objective: To test the hypothesis that the vagus nerve is measurably atrophic in idiopathic Parkinson’s disease (PD). Background: The vagus nerve is discussed to represent…Evaluation of non motor fluctuations in Parkinson disease by a visual analogue scale in Surgical Candidates
Objective: In Parkinson disease (PD) despite the high impact of nonmotor symptoms (NMSs) on patient autonomy and quality of life, evaluation of nonmotor fluctuations (NMF)…Apathy in Parkinson’s disease is associated with REM sleep behavior disorder
Objective: To assess apathy and its relationship with cognitive functions in PD patients with and without Rapid Eye Movement Sleep Behavior Disorder (RBD). Background: Apathy…Olfactory Hallucinations as a Non-motor sign of Parkinson’s disease – A cross-sectional study amongst patients in a tertiary movement center
Objective: Assess the prevalence of olfactory hallucinations (OlfH) in patients presenting to a tertiary movement disorders outpatient clinic. Background: Hallucinations can be considered a non-motor…No differences in the total burden of non-motor symptoms between Parkinson’s disease and non-degenerative parkinsonism
Objective: To compare the total burden of non-motor symptoms between Parkinson's disease and non-degenerative parkinsonism and to study the possible dopaminergic background of these symptoms.…
