Saccades in Parkinson’s disease: Hypometric, slow, or maladaptive?
Objective: Quantitatively study visually-guided saccades (VGS) in Parkinson’s disease (PD). Background: Visuomotor deficits such as hypometric VGS are present in PD despite the retained ability…Modulation of CaMKIIa-NR2B interaction in levodopa-induced dyskinesia in 6-OHDA- lesioned Parkinson’s rats
Objective: In the present study, therefore, we examined the relationship between CaMKII and NR2B in levodopa-induced dyskinesia rats. Background: Long-term treatment with L-dopa leads to…Alpha-synuclein oligomer and rotenone treatments injury the dopaminergic neuron via inhibiting the expression of gene SEMA6D
Objective: To investigate the expression of Semaphorin6D (SEMA6D) and its interaction with Plexin-A1 in cellular Parkinson's disease(PD) models induced by α-synuclein and rotenone. Background: In…Neuropathological correlates of psychiatric disorders in PD
Objective: To test the hypothesis that neuropsychiatric symptoms (NPS) in PD are associated with histopathologically confirmed neuronal loss and gliosis (NLG) in the locus coeruleus…Correlation between mood and behavioral disorders and quality of life in patients with Parkinson’s disease
Objective: The aim of this study was to investigate if the mood and behavioral disorders could be correlate with quality of life in patients with…Depression (BDI-II) in Parkinson’s disease: Prevalence, types, and variables associated to major, minor and subclinical depression in COPPADIS cohort
Objective: To know the prevalence and characteristics of depression in PD patients of the COPPADIS-2015 cohort and its relationship with the other clinical aspects of…Evaluation of affective temperament and bipolarity among patients with Parkinson’ s disease
Objective: To compare the bipolarity and affective temperament scores between patients with Parkinson’s Disease (PD) and healthy controls. Background: Mood disorders are the most common…Pimavanserin Combined With Anti-Dementia Medications for Parkinson Disease Psychosis
Objective: To evaluate the differential antipsychotic effect of pimavanserin, a selective serotonin (5-HT2A) receptor inverse agonist, for Parkinson’s disease psychosis with and without concomitant anti-dementia…Suicide attempts, suicidal and death ideation in Parkinson’s disease
Objective: The objective of this study was to assess the correlates of suicidal and death ideation and suicide attempts in patients with parkinson’s disease. Background:…Erotophonophilia and severe impulse control disorder in a patient with Parkinson’s disease
Objective: N/A Background: Paraphilia a form of hyper sexuality is a rare complication of dopaminergic drugs used in the treatment of Parkinson's disease (PD). We…
