Initial clinical description of progressive supranuclear palsy in the Luxembourg Parkinson’s study
Objective: To characterize the clinical features and prevalence of patients with progressive supranuclear palsy (PSP) in the recently implemented longitudinal Parkinson's cohort (HELP-PD). Background: PSP…Low cerebrospinal fluid 3,4-dihydroxyphenylacetic acid and 3,4-dihydroxyphenylglycol levels are biomarkers of Parkinsonian disorders, including PSP
Objective: To assess whether Progressive Sopranuclear Palsy (PSP) patients show, in CSF an alteration of catecholamine metabolites. Background: It was reported previously that, consistent with…Triple stimulation technique findings in patients with Parkinson’s disease and multiple system atrophy
Objective: This study aims to evaluate the cortico-spinal tract impairment in PD and multiple system atrophy (MSA) Parkinsonian variant using triple stimulation technique (TST). Background:…Clinical phenotype (motor and neuropsychological presentation) and neuroimaging in Sardinian patients affected by atypical parkinsonisms, carriers of 20-22 repeats of C9ORF72 hexanucleotide expansion
Objective: Based on our previous finding of the p.A382T of TARDBP in patients with concomitant parkinsonism in the Sardinian population, we hypothesized that also the…Parkinson’s syndrome as possible manifestation of lamina quadrigemina tumor or inflammation
Objective: Objective of this report is to discuss the case of Parkinson's syndrome (PS) in 22 y.o. patient on the background of the pathological process…Diagnostic value of cardiac 123I-MIBG SPECT and CT co-registration in PD and MSA-P
Objective: The aim of this study was to determine the diagnostic accuracy of cardiac 123I-metaiodobenzylguanidine (MIBG)-SPECT and CT co-registration in discriminating the Parkinson variant of…Innsbruck multiple system atrophy cohort study – An interim analysis
Objective: To characterize the clinical presentation, to identify markers of disease progression and to assess diagnostic utility of 'red flags' in subjects with multiple system…A polysomnography study of REM sleep without atonia and REM sleep behavior disorder in MSA and PD
Objective: The aim of this study was to perform a cross-sectional comparative analysis of quantitative REM sleep without atonia (RWA) and REM sleep behavior disorder…Understanding, predicting, and preventing falls in progressive supranuclear palsy
Objective: To (1) evaluate which factors are associated with increasing falls in Progressive Supranuclear Palsy (PSP), unrelated to freezing; and (2) subsequently develop a predictive…Brain structural abnormalities in multiple system atrophy patients with cognitive impairment
Objective: To investigate the cerebral anatomical changes associated with cognitive impairment (CI) in multiple system atrophy (MSA). Background: Mild cognitive deficits are frequently reported in…