Parkinson’s disease-associated Miro1 mutants cause mitochondrial dysfunction
Objective: In the present study we dissected the role of the first PD-associated mutations in RhoT1, the gene encoding for Miro1. Background: Commonly involved pathogenic…A descriptive study on the safety and feasibility of mesenchymal stem cell therapy for Parkinson’s disease: A case series
Objective: To describe the incidence and severity of infusion-related adverse events of mesenchymal stem cells (MSC) for Parkinson's disease in patients who underwent treatment. Background:…Polyethylenimine (PEI) nanoparticle-mediated delivery of siRNA to silence neuronal gene expression of alpha-synuclein in a mouse model of Parkinson’s disease
Objective: To develop novel therapeutic strategies for movement disorders by interfering with neuronal gene expression, PEI nanoparticle-mediated delivery of RNA was investigated in vivo. Background:…Gene delivery of AAV2-neurturin for patients with Parkinson’s disease: A meta-analysis
Objective: The objectives of this meta-analysis are: 1) to investigate the efficacy of AAV2-neurturin gene delivery for patients with Parkinson's disease; 2) to compare AAV2-neurturin…Two-step induction of dopaminergic neurons – Differentiation of leukapharesis-derived mesenchymal stem cells
Objective: The aim of the present study is to establish a reproducible in-vitro protocol to induce the human MSCs derived from peripheral blood, after mobilization…Differentiated versus undifferentiated mesenchymal stem cell therapy in paraquat model of Parkinson’s disease
Objective: To investigate the effect of undifferentiated versus differentiated CD34 stem cells series on paraquat model of PD and to elucidate the mechanism of action…Gene expression analysis using the Parkinson’s disease map reveals early effects of alpha-synuclein on PD pathogenesis
Objective: The identification of early disease markers for Parkinson's disease (PD) is essential, since the disease is already in an advanced state when motor symptoms…Integrity of the superior longitudinal fascicle and its relationship with anticipatory postural adjustments in people with Parkinson’s disease and freezing of gait
Objective: To assess the integrity of the Superior Longitudinal Fascicle (SLF) and its relationship with the Anticipatory Postural Adjustments (APAs) of step initiation in people…Relationships of cognitive functions and psychiatric symptoms with motor phenotypes in patients with untreated early-stage Parkinson’s disease
Objective: It has been shown that the clinical types of Parkinson's disease (PD) based on motor symptoms include motor phenotypes of postural instability and gait…Staging and clinical correlates of cortical thinning in Parkinson’s disease
Objective: By using a novel disease staging model to investigate the progression and clinical associations of cortical thinning in Parkinson's disease (PD) patients. Background: The…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.