MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Increased anti-MAG autoantibodies titers in Parkinson’s disease

    E. Papuc, K. Rejdak (Lublin, Poland)

    Objective: To search for biomarkers of neurodegenerative process in Parkinson's disease (PD).There is emerging evidence that humoral response may be involved in the pathogenesis and…
  • 2016 International Congress

    Toward a new biomarker on Parkinson’s disease: Study of alpha synuclein on upper enteric system by endoscopy

    N. Ben Ali, S. Mrabet, S. Hawet, R. Debbiche, S. Belal (Tunis, Tunisia)

    Objective: The aim of our study was to investigate the alpha synuclein deposition at the enteric nerve system on patient with Parkinson's disease and provide…
  • 2016 International Congress

    Alpha-synuclein in gastric and colonic mucosa in Parkinson’s disease: Limited role as a biomarker

    S.J. Chung, J. Kim, H.J. Lee, H.S. Ryu, K.W. Jung, M.J. Kim, M.J. Kim, S.M. Hong, S.J. Myung (Seoul, Korea)

    Objective: We aimed to investigate the utility of alpha-synuclein (α-SYN) immunoreactivity from gastric and colonic mucosal tissues obtained by routine endoscopy to detect Parkinson's disease…
  • 2016 International Congress

    Longitudinal measurements of cerebrospinal fluid biomarkers in Parkinson’s disease

    S. Hall, Y. Surova, A. Öhrfelt, K. Blennow, H. Zetterberg, O. Hansson (Lund, Sweden)

    Objective: To investigate whether cerebrospinal fluid (CSF) levels of tau, phosphorylated tau, β-amyloid42, α-synuclein, neurofilament light and YKL-40 change over time and if changes correlate…
  • 2016 International Congress

    Objective methods for quantifying the deep brain stimulation (DBS) efficacy in subthalamic-nuclei (STN) neurons with microelectrode recording (MER) technology

    V.R. Rama Raju, R.K. Mridula, R. Borgohain, V. Rama Raju (Hyderabad, India)

    Objective: To design a computational modeling to develop a new diagnostic tool for effective neuro-medical-diagnostics for end users, to investigate and evaluate the potential benefits…
  • 2016 International Congress

    Counteracting PINK1/parkin deficiency by activating alternative mitophagic pathway: a potential therapeutic intervention for Parkinson’s disease

    B. Koentjoro, J.S. Park, C.M. Sue (Sydney, Australia)

    Objective: To identify a new therapeutic target for developing neuroprotective treatment in Parkinson's disease (PD) by improving mitochondrial function through restoration of mitochondrial quality control…
  • 2016 International Congress

    Physical training prevents depressive-like behavior and bdnf decrease in an animal model of Parkinson’s disease

    T. Tuon, S.S. Valvasori, J.L. Quevedo, C.T. Souza, R.A. Pinho (Criciúma, Brazil)

    Objective: The aim of this study was to investigate the effects of two types of physical training on depressive-like behavior and pro-BDNF, BDNF and its…
  • 2016 International Congress

    Speed and severity of toxicity induced by pre-formed α-synuclein fibrils in rat brain is enhanced by α-synuclein overexpression

    P. Thakur, L. Breger, B. Mattsson, K. Luk, V.M. Lee, J. Trojanowski, A. Björklund (Lund, Sweden)

    Objective: To develop a physiologically relevant model of PD. Background: Intracerebral injection of pre-formed α-synuclein fibrils has emerged as an interesting tool to induce PD-like…
  • 2016 International Congress

    SOD1 aggregation: A pathological link between Parkinson’s disease and amyotrophic lateral sclerosis?

    B.G. Trist, K.M. Davies, S. Genoud, V. Smoothy, G.M. Halliday, S. Roudeau, A. Carmona, L. Perrin-Verdugier, R. Ortega, K.L. Double (Sydney, Australia)

    Objective: To characterize (1) a novel association between superoxide dismutase 1 (SOD1) aggregation and neuronal loss in the Parkinson's disease (PD) brain and (2) the…
  • 2016 International Congress

    Cerebellar atrophy in Parkinson’s disease and its implication for network connectivity

    J.M. Shine, C. O'Callaghan, M. Hornberger, G.M. Halliday, S.J.G. Lewis (Palo Alto, CA, USA)

    Objective: To determine the effect of cerebellar atrophy on resting-state network abnormalities in individuals with Parkinson's disease. Background: In Parkinson's disease, the cerebellum is a…
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