Botulinum Neurotoxin (BoNT) for treatment of functional (psychogenic) jerky movement disorders: a randomized placebo-controlled clinical trial
Objective: To assess the effectiveness of botulinum neurotoxin (BonT) in patients with functional jerky movement disorders Background: At least 2–9% of patients seen in movement…Antibody-Induced Failure of Botulinum Toxin Therapy: Restart with Incobotulinumtoxina Offers a New Opportunity
Objective: To study whether incobotulinumtoxinA (INCO), a new, low-antigenicity botulinum toxin (BT) drug, increases BT antibody (BTAB) titers in patients with antibody-induced therapy failure (ABTF)…Intracerebroventricular administration of dopamine: A new therapeutic concept for Parkinson’s disease?
Objective: In this study, we aim to demonstrate that continuous i.c.v. infusion of dopamine close to the striatum is a feasible and highly efficient treatment…Focused ultrasound subthalatomy restores intracortical inhibition in PD
Objective: To test the effects of focused ultrasound subthalatomy on motor cortex excitability in Parkinson’s disease (PD). Background: Short-interval intracortical inhibition (SICI), a GABAAR-mediated inhibition…Intranasal delivery of insulin for the restoration of memory signaling in Alzheimer disease
Objective: Objective of this study is to develop delivery-system to overcome BBB by employing novel, non-invasive approach via nasal route. The olfactory neural pathway provides…Multidisciplinary Parkinson rehabilitation delays nursing home admission and is cost-effective.
Objective: The purpose of this program was to analyze whether activities of daily living (ADL) could be improved, thereby delaying definite nursing home admission and…AAV-mediated over-expression of VEGF-B in PINK1 gene knockout rats increases striatal dopamine content
Objective: To evaluate overexpression of the neuroprotective vascular endothelial growth factor B (VEGF-B) in a genetic Parkinson’s disease (PD) model. Background: We have shown in…Exercise preferences of people with Parkinson’s disease: preliminary findings of a discrete choice experiment
Objective: To identify which exercise program attributes most commonly drive willingness of people with Parkinson’s disease (PD) to participate in evidence-based exercise programs. Background: A…Impact of weekly dance classes on quality of life of individuals with Parkinson’s Disease.
Objective: The aim of the present study is to investigate the short-term effects of weekly dance classes on the Quality of Life (QOL) of PD…A model community neurofitness and wellness center for people with Parkinson disease. 1-year group pilot data
Objective: Report preliminary one-year benefits of ongoing research-based community group exercise programs integrated with 6-month therapy coaching for people of varying disease severity (to date,…
