MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Early grey matter changes in structural covariance networks in Huntington’s disease

    E.M. Coppen, J. van der Grond, A. Hafkemeijer, S.A.R.B. Rombouts, R.A.C. Roos (Leiden, Netherlands)

    Objective: To identify network integrity changes in Huntington's disease (HD) using grey matter whole brain structural covariance networks and to examine relationships between anatomical networks…
  • 2016 International Congress

    Progression of motor subtypes in Huntington’s disease: A six-year follow-up

    M. Jacobs, E.P. 't Hart, R.A.C. Roos (Leiden, Netherlands)

    Objective: To investigate the course of motor symptoms in Huntington's disease (HD) and their relationship with cognitive- and general functioning over time. Background: The motor…
  • 2016 International Congress

    Dysphagia in early stage Huntington’s disease (HD) – Pilot observations from a multimodal imaging study

    I. Trender-Gerhard, E. Michou, A. Gerhard, D. Craufurd, S. Hamdy, K. Herholz (Manchester, United Kingdom)

    Objective: To assess the central neural control of swallowing in HD patients with mild dysphagia using a multimodal imaging approach combining qualitative and quantitative swallowing…
  • 2016 International Congress

    Abnormal intrinsic brain activity reveals neural correlates of impaired cognitive function in early stage of Huntington’s disease (HD): A resting-state fMRI study

    W. Liu, J. Yang, K. Chen, C. Luo, J.M. Burgunder, Q. Gong, H. Shang (Chengdu, People's Republic of China)

    Objective: To better understand the mechanism underlying cognitive impairment in HD. Background: Cognitive impairment can precede the motor symptoms and deteriorates over time in HD…
  • 2016 International Congress

    Cognitive impairment in Huntington’s disease

    N. Kamble, N. Netravathi, K. Kumar, S. Jain, P.K. Pal (Bangalore, India)

    Objective: The present study was done to assess cognitive impairment in HD patients using a neuropsychological battery and to correlate with clinical severity and CAG…
  • 2016 International Congress

    Verbatim patient-reported outcomes and trails making test B (TMT-B) performance in the REACH2HD trial

    J.L. Purks, A. Zeymo, N.M. Shara, K.E. Anderson, I. Shoulson (Washington, DC, USA)

    Objective: Examine the relationship between Trails Making Test B (TMT-B) performance and bothersome cognitive complaints among Huntington Disease (HD) research participants in the REACH2HD randomized-controlled…
  • 2016 International Congress

    Cortico-striatal functional connectivity in the premanifest and manifest period of Huntingtons disease measured with high-field functional magnetic resonance imaging

    M. Kronenbuerger, J. Hua, C.A. Ross (Baltimore, MD, USA)

    Objective: To assess functional connectivity in the premanifest and manifest period of Huntington's disease (HD) by using functional Magnetic Resonance Imaging (fMRI) at high-field (7…
  • 2016 International Congress

    Striatal molecular alterations in Huntington’s disease gene expansion carriers: A systematic review and meta-analysis of PET studies

    F. Niccolini, G. Pagano, P. Fusar-Poli, A. Wood, L. Mrzljak, C. Sampaio, M. Politis (London, United Kingdom)

    Objective: To systematically examine the evidence of striatal molecular alterations in premanifest and manifest Huntington's disease gene expansion carriers (HDGECs) as measured by Positron emission…
  • 2016 International Congress

    Tau pathology in Huntington’s disease: A brief in vivo PET-imaging report

    K. Giehl, K. Reetz, I. Dogan, C. Werner, J.B. Schulz, A. Drzezga, T. van Eimeren (Köln, Germany)

    Objective: To assess feasibility of measuring pathological tau deposition in patients with Huntington's disease (HD) using [18F]-AV-1451 (f.k.a. T807) PET. Background: HD is a progressive…
  • 2016 International Congress

    Dysregulations of GABAergic neurotransmission in Huntington’s disease brain

    Y.T. Hsu, Y.G. Chang, H.M. Chen, Y. Chern (Taichung, Taiwan)

    Objective: To investigate (1) the expression of GABAA receptors and KCC2 in both Huntington's disease (HD) mouse models and patients and (2) the inhibitory effect…
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