Expanding Parkinson’s Disease Genomics in East Africa
Objective: To establish a deeply phenotyped Parkinson’s disease (PD) cohort in East Africa and generate genomic and biosample resources for discovery and replication of ancestry-specific…Quantitative Analysis of the DESH in Normal Pressure Hydrocephalus and Parkinson’s Disease
Objective: To investigate whether Parkinson’s disease (PD) exhibits imaging features similar to normal pressure hydrocephalus (NPH) by comparison with healthy controls and NPH patients, and…Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion in Advanced Parkinson’s Disease: Results from a Prospective Real-world Study
Objective: To evaluate the effectiveness and tolerability of continuous subcutaneous foslevodopa/foscarbidopa (LDp/CDp) infusion in patients with advanced Parkinson’s disease (PD) in a real-world setting. Background: In…Functional Neurological Disorder And Anti-GAD65–Associated Autoimmune Neurological Disease: Diagnostic Overlap In A Retrospective Case Series
Objective: To describe the characteristics of functional neurological disorder (FND) in patients with anti-GAD65–associated autoimmune neurological disease (antiGAD65 AAND) Background: The global prevalence of FND…Diffusion MRI Markers of Neural Reserve: Interaction Between Callosal Integrity and Clinical Vulnerability After Functional Neurosurgery in Parkinson’s Disease
Objective: To evaluate whether diffusion MRI markers of callosal integrity, together with baseline clinical vulnerability, are associated with cognitive trajectory after functional neurosurgical treatment in…Computer Vision for Quantitative Assessment of Posture and Instability in Parkinson’s Disease
Objective: To investigate whether markerless computer vision can objectively quantify axial symptoms in Parkinson’s disease (PD), focusing on posture and instability. Background: Axial symptoms such…Comparison of Neuroimaging-Derived and Clinical Motor Subtypes in Early Parkinson’s Disease
Objective: To evaluate diffusion MRI-derived extracellular free water (isotropic diffusion [ISO]) in subcortical motor regions and compare data-driven ISO-based subtypes with clinically defined tremor-dominant (TD),…Baicalein Attenuates Rotenone-Induced Neurodegeneration by Regulating BDNF/CREB/Akt Signaling in Parkinson’s Disease
Objective: To evaluate the therapeutic potential of baicalein and to investigate its underlying neuroprotective mechanism in a rotenone-induced mouse model of Parkinson’s disease. Background: Parkinson’s…Differentiation of Parkinsonian Syndromes Using Cognitive Strategies and Associations with Non-tremor Motor Progression
Objective: This study aims to investigate whether cognitive strategies on verbal fluency tasks differentiate Parkinson’s disease (PD) from Progressive Supranuclear Palsy (PSP) and healthy adults, and are associated with the progression of clinical motor symptoms in Parkinson’s…Smartphone Video-Based Finger Tapping Analysis Using Machine Learning for Parkinson’s Disease Classification
Objective: To evaluate the accuracy of a machine learning model using smartphone-captured finger tapping videos to distinguish patients with Parkinson's disease (PD) from healthy controls…
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