In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Assessing vestibular function in individuals with cervical dystonia and the effects of botulinum toxin treatment
Objective: To determine if individuals with cervical dystonia have altered vestibular function compared to unaffected individuals, and whether botulinum toxin treatment alters those variables. Background:…Differences in processing proprioceptive input from the neck muscles may explain the benefit from sensory tricks in patients with idiopathic cervical dystonia
Objective: We used a paradigm of neck vibration to test the hypothesis that the sensory trick (ST), which is used by some patients with idiopathic…Striatal postsynaptic dysfunction in X-linked dystonia-parkinsonism is associated with disease progression
Objective: To assess pre- and postsynaptic dopaminergic function in X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP) is a neurodegenerative adult-onset movement disorder associated with striatal…Multi-parameter imaging in hemidystonia responsive to GPi deep brain stimulation
Objective: To present i) imaging data in a case of hemidystonia using structural (diffusion tensor imaging-DTI and fiber tractography-FT) and functional (functional MRI-fMRI and magnetoencephalography-MEG)…Chewing-induced blepharospasm in Parkinson’s disease
Objective: Report and discuss a rare presentation of BS. Background: Dystonia is described in untreated Parkinson's disease (PD) patients and is also one of the…Real-time ultrasound for automated analysis and visualization of neck muscles in cervical dystonia
Objective: To demonstrate an automated ultrasound-based method for real-time visualization of neck muscles in cervical dystonia. Background: Understanding of the pattern and extent of muscle…The sense of agency is altered in cervical dystonia
Objective: We investigated whether deficits in motor representation are associated with alterations of the sense of agency in dystonic patients. Background: Abnormalities of the cognitive…Temporal dynamics of pallidal low-frequency oscillations in dystonia
Objective: To assess the occurrence and volatility of 4-12 Hz oscillations in local field potentials (LFPs) recorded in the internal globus pallidus (GPi) of dystonia…Therapeutic potential of compounds preferring specific GABAA receptor subunits for the treatment of dystonia?
Objective: To further define the pathophysiology of the reduction of striatal interneurons in an animal model of dystonia and to develop novel therapeutic strategies targeting…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.