Evaluation of the accuracy of stereotactic DBS electrode implantation by post-operative image fusion
Objective: The precision in implantation of deep brain stimulation (DBS) electrodes based on pre-operative MRI planning is of utmost importance for the success of this…Impact of the combined depletion of monoamines on the effectiveness of deep brain stimulation of the subthalamic nucleus
Objective: To investigate the involvement of combined depletions of dopamine, norepinephrine and serotonin in the manifestation of motor and non-motor deficits and their impact on…A dopamine-dependent activity of the STN in the control of balance in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN), and its relation to nigro-striatal dopaminergic denervation, in control of balance in Parkinson's disease (PD).…Cortical and subcortical contribution in the production of reaching movements in Parkinson’s disease
Objective: To investigate the interplay between subthalamic nucleus (STN) activity and striatal dopamine deficiency in the production of arm movements in subjects with Parkinson's disease…A prospective study of patients’ expectations in subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To prospectively assess the long-term outcome of subthalamic nucleus (STN) deep brain stimulation (DBS) and the relationship with patients' expectations and satisfaction. Background: Subthalamic…Is the PPN a valuable target for deep brain stimulation in treatment of Parkinsonian disorders? Experience of a patient’s series
Objective: Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been reported to improve motor symptoms in idiopathic (IPS) and in atypical Parkinsonian syndromes…In vivo validation of a new wireless portable stimulator for chronic deep brain stimulation in freely moving rats
Objective: To develop a new dedicated stimulator, adapted for chronic experiments on rodent models and that mimics the conditions of DBS human therapy: bilateral, current-controlled…Airway protective mechanisms and deep brain stimulation in Parkinson’s disease
Objective: The goal of this study was to compare the effects of STN vs. GPi DBS on swallowing and cough outcomes in PD. Background: Deep…Improving parkinsonism in DBS poor-responders by surgical lead revision of subthalamic electrodes
Objective: If subthalamic deep brain stimulation (STN-DBS) results in poor symptom control or adverse side effects at low stimulation threshold surgical lead revision for optimal…Single versus multiple microelectrode recordings (MER) in STN-DBS-surgery for PD: A randomized double-blind controlled trial
Objective: To evaluate whether using multiple versus single MER-guidance peroperatively influence improvement of motor symptoms by STN-DBS in advanced PD. Background: It is well established…
