Nilotinib significantly alters CSF biomarkers and increases endogenous dopamine in open-label phase I clinical trial in Parkinson’s disease with dementia and Lewy body dementia
Objective: The objective was to determine whether Nilotinib crosses the blood brain barrier (BBB). Background: Parkinson's disease (PD) involves death of dopamine producing neurons in…Efficacy and feasibility study of the Medido eletronic medication dispenser in Parkinson’s disease: A multicentre randomized controlled trial
Objective: The aim of this randomized controlled study was to assess the effect of the electronic medication dispenser, Medido, on physical limitations in PD. Background:…Day case initiation of subcutaneous apomorphine in people with Parkinson’s disease: A retrospective analysis from a UK teaching hospital
Objective: To evaluate a cohort of people with Parkinson's disease (PD) who were initiated on subcutaneous apomorphine injections or continuous subcutaneous apomorphine infusions (CSAI) on…Effects of combined repetitive transcranial magnetic stimulation and treadmill training on gait performance in Parkinson’s disease
Objective: To evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) with treadmill training on walking performance and corticomotor excitability in people with Parkinson's disease…Peri-operative dopaminergic replacement protocol with rotigotine in Parkinson’s disease patients
Objective: To evaluate the accomplishment of a peri-operative dopaminergic replacement protocol established in our centre from 2011 to 2014, and analyse the main factors associated…Group climate in the voice therapy of patients with Parkinson’s disease
Objective: To examine the impact of coaching and group dynamics activities in the voice, speech and communication of Parkinson's disease (PD) patients, as well as…Speech and voice range profile in patients with Parkinson’s disease with deep brain stimulation: Preliminary data
Objective: To assess the use of Voice Range Profile(VRP) and Speech Range Profile(SRP) in the evaluation of patients with on and off Deep brain stimulation(DBS).…Effect of over(exaggerated) articulation technique in voice and speech of individuals with Parkinson’s disease with deep brain stimulation
Objective: To investigate the immediate effect and after 15minutes(min) of over articulation technique in individuals with Deep Brain Stimulation(DBS). Background: Studies evaluating the immediate effects…Preclinical evaluation of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias: Is it a ‘chemical’ DBS?
Objective: To evaluate mechanism of long-term activity of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias (LID). Background: Ketamine is an anesthetic that, when administered as…The clinical effects of mucuna and green tea in combination with levodopa-benserazide in advanced Parkinson’s disease: Experience from a case report
Objective: To describe the clinical effects of combined natural dopaminergic drugs with conventional levodopa therapy in a PD patient with motor and non-motor complications. Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.