Inhibition of glucosylceramide synthase reduces pathology and improves cognition in synucleinopathy murine models
Objective: We investigated the merits of glucosylceramide synthase (GCS) inhibition as a potential treatment for synucleinopathies. Background: Mutations in GBA, the gene encoding glucocerebrosidase, are…Correlation between Parkinson’s disease and malignant tumors
Objective: We have carried out the research among the group of Sardinian patients with PD, led by our Ambulatory of Movement Disorders, to evaluate the…Real world conversion of levodopa to a novel extended release levodopa preparation: Determining predictors and dose ratios
Objective: To determine predictors of response and conversion ratios for a novel extended release levodopa preparation. Background: A new extended release levodopa preparation, Rytary®, has…Virtual-reality balance training with Nintendo-Wii games improves dynamic balance in Parkinson’s disease patients
Objective: This study was to investigate the effectiveness of a 8-week virtual reality exercise program designed around the Nintendo Wii (Wii), in improving balance among…Recent result of indicative evaluation for deep brain stimulation of Parkinson’s disease patients
Objective: To report recent result of indicative evaluation for deep brain stimulation (DBS) of Parkinson's disease (PD) patients, ant to investigate relationship between pathological condition…Multidisciplinary Parkinson rehabilitation in the Netherlands: The effectiveness of points of Parkinson (POP)
Objective: To analyze the effect of the POP rehab program for advanced PD patients on motor- and non-motor symptoms up to 2 years and determine…The role of the frontal lobe in complex walking among healthy older adults and patients with Parkinson’s disease: An fNIRS study
Objective: To investigate the role of the frontal lobe during dual tasking and obstacle negotiation, in healthy older adults and patients with Parkinson's disease (PD).…Visual hallucination and pattern of brain degeneration in Parkinson’s disease
Objective: This study was aimed to reveal pattern of brain degeneration related to visual hallucination (VH) throughout different stages of PD. Background: Previous neuroimaging studies…Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Neuromelanin in Parkinson’s disease: A 3 T MRI study
Objective: The purpose of this study was to investigate whether the signal intensity of the substantia nigra pars compacta (SNc) and locus coeruleus (LC) on…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.