Duodopa treatment experience in Oradea
Objective: We want to present our results in Duodopa treatment for advanced Parkinson's disease (PD). Background: A center for advanced PD was created in our…Effectiveness of a multidisciplinary PD clinic in improving quality of life
Objective: To evaluate the effectiveness of a multidisciplinary PD clinic in a tertiary hospital in Hong Kong. Background: Parkinson's disease (PD) has been recognized as…Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3beta activity
Objective: To identify disease-modifying therapy for LRRK2-G2019S parkinsonism. Background: Leucine-rich repeat kinase 2 (LRRK2) is the most common genetic cause of Parkinson's disease (PD) without…Predicting therapeutic effects of atomoxetine and citalopram on response inhibition in Parkinson’s disease
Objective: (1) To reassess the behavioral impact of novel noradrenergic (atomoxetine) and serotonergic (citalopram) therapies for impulsivity and (2) to develop predictive models to identify…Telemedicine facilitates efficient and safe home titration of levodopa/carbidopa intestinal gel (LCIG) in patients with advanced Parkinson’s disease
Objective: To demonstrate feasibility of TM for LCIG home titration, evaluate resource use, and assess patient, neurologist and nurse satisfaction. Background: LCIG, is used for…Safety, pharmacokinetics, and efficacy of levodopa prodrug ONO-2160/CD: A study in patients with Parkinson’s disease
Objective: The objective of this study was to evaluate the safety, pharmacokinetic profile, and efficacy of ONO-2160/carbidopa (CD) and to compare them with an immediate-release…Effects of levodopa on adaptation of reactive stepping in people with Parkinson’s disease
Objective: Participants with PD were able to improve postural stepping responses with practice and this learning was improved by levodopa. Background: Protective steps in response…A double blind investigation of efficacy and safety of incobotulinumtoxinA in Parkinson’s disease tremor- A customized injection approach
Objective: To evaluate the safety and efficacy of incobotulinumtoxinA (IncoA) injection in the tremor of Parkinson's disease (PD). Background: Unlike other cardinal motor features of…Adenosine A2A receptor antagonist istradefylline might have efficacy to fatigue and depression in some patients of Parkinson’s disease
Objective: To evaluate the efficacy of istradefylline, a selective adenosine A2A receptor antagonist, for fatigue and depression in Parkinson's disease (PD) patients. Background: Istradefylline is…Voice harmonic amplitude differences before and after LSVT LOUDTM in Parkinson’s disease
Objective: To evaluate voice harmonic amplitudes from acoustic spectra of speech produced by subjects with Parkinson's disease (PD) before and after voice treatment, in order…