Does Knowing More Mean Tolerating More? Satisfaction with Medication Information and Levodopa Dosage in Parkinson’s Disease
Objective: To characterize the correlation between satisfaction with medication-related information and daily levodopa dosage in Parkinson’s disease (PD) patients presenting with levodopa-related complaints. Background: Adequate…Binge-eating as an Initial Presentation for the Diagnosis of Chorea-acanthocytosis
Objective: - Background: Chorea-acanthocytosis (ChAc) is an autosomal recessive disorder associated with mutations or deletions in the VPS13A gene on chromosome 9q21, which codes for…Genetic determinants of cognitive performance in Parkinson’s disease: impact of distal regulatory variation at the SNCA locus in the gp2 cohort
Objective: This study evaluates the association between a distal regulatory haplotype at the SNCA locus and cognitive performance, measured by the Montreal Cognitive Assessment (MoCA),…Expanded Parkinson’s Disease GWAS in African Ancestry Populations Identifies Novel Risk Loci and Precision Medicine Targets
Objective: To conduct the largest genome-wide association study (GWAS) of Parkinson's disease (PD) in African (AFR) and African admixed (AAC) ancestry populations to identify ancestry-specific…Lipid Alterations in Central Nervous System and Plasma During Early Stages of Parkinson’s Disease
Objective: To identify early lipid alterations in a progressive mouse model of Parkinson’s disease (PD) and to determine whether peripheral lipid signatures reflect lipid changes…Chinese Expert Consensus and Recommendations on Sensing-guided Deep Brain Stimulation for Parkinson’s Disease: A Modified Delphi Study
Objective: To propose some well-accepted recommendations on sensing-guided deep brain stimulation for Parkinson's Disease. Background: Deep brain stimulation (DBS) has been widely accepted as a well-established neurosurgical…Childhood-onset Dystonia Linked to KIF5A:p.Arg422Cys: Case Report and Functional Characterization
Objective: To describe the clinical and functional characterization of a patient with childhood-onset dystonia carrying the KIF5A:p.Arg422Cys variant. Background: KIF5A encodes a neuronal kinesin essential…Large-Scale Shotgun Mass Spectrometry in Parkinson’s Disease Plasma Identifies Novel Biomarker Candidates
Objective: To identify novel Parkinson’s disease (PD) blood biomarkers using unbiased shotgun mass spectrometry. Background: PD is a common neurodegenerative disorder diagnosed based on its…Iatrogenic akathisia aggravating depressive and psychotic symptoms: a case report
Objective: To highlight the clinical impact of drug-induced akathisia on affective, psychotic, and cognitive symptoms and the importance of recognizing it in psychiatric practice. Background:…Detecting Parkinson’s Disease with Postural Sway via Single IMU and Machine Learning
Objective: To determine whether simple standing balance tasks, assessed using a single wearable inertial measurement unit (IMU), can effectively differentiate individuals with Parkinson’s disease (PD)…
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