MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Cholinergic activity associates with cognitive function in PD using [18F]VAT

    J. O'Donnell, A. Eid, H. Hwang, S. Grossen, J. Hood, E. Foster, Z. Tu, J. Perlmutter, M. Campbell (St. Louis, USA)

    Objective: To map the relationship between cholinergic activity in Parkinson Disease (PD) and cognitive performance and identify any differences in this relationship in cognitive impairment.…
  • 2025 International Congress

    Semi-quantitative Evaluation of Midbrain Accumulation in 123I-FP-CIT SPECT in Parkinson’s disease and Parkinsonian Syndromes

    T. Totsune, T. Baba, Y. Sugimura, H. Oizumi, H. Tanaka, T. Takahashi, M. Yoshioka, K. Nagamatsu, T. Hasegawa, A. Takeda (Sendai, Japan)

    Objective: To establish a method for evaluating midbrain accumulation of 123I-FP-CIT SPECT and assess its ability to differentiate between Parkinson’s disease (PD) and Parkinsonian syndromes…
  • 2025 International Congress

    Continuous Subcutaneous Dopaminergic Stimulation: Exploring the impact of Foslevodopa/Foscarbidopa on Gait in Parkinson’s disease.

    C. O'Keeffe, J. Inocentes, M. Bradley, A. Gallagher, F. Ruggieri, R. Walsh, T. Lynch, R. Reilly, C. Fearon (Dublin, Ireland)

    Objective: The primary objective of this study is to investigate the effect of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (FL/FC) on gait in those with…
  • 2025 International Congress

    Inpatient Multimodal Intensive Care in Moderately Advanced Parkinson’s Disease: Role Of Medication Adjustment In Outcome Measures

    N. Elayan, L. Rubin, M. Mccrossin, C. Roberts, H. Shakil, A. Di Rocco, M. Ghilardi (Long Island, USA)

    Objective: In this study, we wish to determine whether medication changes play a major role in the improvements observed after in-patient multimodal intensive neurorehabilitation and…
  • 2025 International Congress

    Impact of Aquaporin-4 polymorphisms on Glymphatic Function and Motor Symptoms in Parkinson’s Disease

    J. Qin, M. Zhang (Hangzhou, China)

    Objective: This study aims to investigate whether single-nucleotide polymorphisms (SNPs) of the Aquaporin-4(AQP4) gene were related to abnormal protein accumulation (α-synuclein), glymphatic dysfunction (DTI-ALPS), and…
  • 2025 International Congress

    Fatty Acid Metabolic Reprogramming Regulates Glial-Epithelial Axis via Nur77 Palmitoylation in Intestinal Dysfunction in Parkinson’s Disease

    J. Zou, Z. Deng, Z. Lu, X. Luo, F. Yu, W. Bi (Guangzhou, China)

    Objective: This study aims to elucidate the regulatory role of stearoyl-CoA desaturase 1 (SCD1) in Parkinson’s disease (PD)-associated intestinal dysfunction, focusing on its mechanism in…
  • 2025 International Congress

    Assessing Genome-wide Genetic Risk for Parkinson’s Disease Age at Onset in European Sub-Populations: from the Global Parkinson’s Genetics Program

    GP2. Parkinson'S_genetics_program (Bethesda, USA)

    Objective: To identify the genetic determinants of Parkinson’s disease (PD) age at onset (AAO) within and across genetically determined European ancestries (European, Ashkenazi Jewish, Finnish,…
  • 2025 International Congress

    Clinical Profile and 18F -Fluorodopa Positron Emission Tomography (18F -DOPA PET) Findings in a Movement Disorder Clinic Patient Cohort

    S. Yellaturi, M. Prabhu, A. Behera, S. Pandey (Faridabad, India)

    Objective: This study aimed to evaluate the utility of 18F -DOPA PET in patients with diagnostic uncertainty at our movement disorder clinic in India. Background:…
  • 2025 International Congress

    Effects of Exogenous Melatonin on Sleep and Motor Symptoms in Parkinson’s Disease: A Systematic Review and Meta-Analysis

    M. Alghaniem, A. Abunamoos, F. Qtaishat, A. Rababah, M. Abu Hasna, Y. Aljazi, M. Mustafa, F. Alnajjar, T. Patel, N. Hamam (Amman, 11942, Jordan)

    Objective: To evaluate melatonin's efficacy in enhancing sleep and motor symptoms in Parkinson’s disease (PD) through an updated systematic review and meta-analysis. Background: Sleep disturbances…
  • 2025 International Congress

    Association of Mitochondrial DNA Haplogroup and pS65-Ub Levels in Lewy Body Disease

    N. Tran, X. Hou, M. Heckman, F. Fiesel, S. Koga, D. Dickson, W. Springer, O. Ross (Jacksonville, USA)

    Objective: To determine whether specific mitochondrial DNA (mtDNA) haplogroup(s) affect the level of p-S65-Ub as quantitative marker of mitochondrial damage in Lewy Body Disease. Background:…
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