STOP-TIC Updates: Strengthening Tourette Treatment Options using TMS to Improve CBIT: A randomized sham-controlled trial
Objective: To determine if accelerated repetitive transcranial magnetic stimulation (rTMS) will augment Comprehensive Behavioral Intervention for Tics (CBIT) for Tourette Syndrome (TS) symptoms. Background: rTMS…Therapeutic effects of intermittent theta-burst stimulation on motor, non-motor symptoms and functional connectivity in de novo Parkinson’s disease
Objective: To evaluate the clinical and resting-state functional connectivity effects of bilateral M1-iTBS in patients with de novo Parkinson’s disease. Background: Dopaminergic neurodegeneration in Parkinson’s…Genetic determinants of cognitive performance in Parkinson’s disease: impact of distal regulatory variation at the SNCA locus in the gp2 cohort
Objective: This study evaluates the association between a distal regulatory haplotype at the SNCA locus and cognitive performance, measured by the Montreal Cognitive Assessment (MoCA),…Beyond Motor Symptoms: Utilizing the FreeSurfer Brainstem Substructures Module to Characterize a Complex Parkinsonian Phenotype with Profound Dysautonomia
Objective: To describe the autonomic function profile and quantitative brainstem substructures analysis in a 62-year-old male of Parkinsonism complicated by severe autonomic failure and neuropsychiatric…Hyperkinetic Movement Disorder as the First Manifestation of Gaucher Disease Type 3
Objective: Gaucher disease, an autosomal recessive lysosomal storage disorder, is caused by a deficiency of the enzyme glucocerebrosidase. This results in the accumulation of glucosylceramide…Binge-eating as an Initial Presentation for the Diagnosis of Chorea-acanthocytosis
Objective: - Background: Chorea-acanthocytosis (ChAc) is an autosomal recessive disorder associated with mutations or deletions in the VPS13A gene on chromosome 9q21, which codes for…Neuromelanin Loss Is Associated with Increased Substantia Nigra Free-Water: a Longitudinal Study of Controls, RBD, and PD
Objective: To longitudinally characterize substantia nigra (SN) neuromelanin (NM) and free-water (FW) MRI biomarkers by comparing control, REM sleep behaviour disorder (RBD), and Parkinson’s disease…Factors Associated with Efficacy and Safety of Unilateral Thalamic MRgFUS in Essential Tremor: A Single-Center Cohort Study
Objective: To identify factors associated with treatment efficacy and safety of unilateral thalamic magnetic resonance-guided focused ultrasound (MRgFUS) in patients with essential tremor (ET). Background:…18F-FD4 PET Reveals α-Synuclein Deposition and Clinical Correlations in Multiple System Atrophy
Objective: This study aimed to determine the potential of 18F-FD4 PET to serve as an in vivo pathology mapping tool for MSA, providing initial proof-of-concept for its use in…Automated differential diagnosis of Parkinson’s disease and Parkinson-like disorders via motion capture analysis
Objective: The objective of this study is to establish a foundation for an automated differential diagnostic system for Parkinson’s disease (PD) and Parkinson-like disorders (PL)…
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