MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Gray Matter Microstructural Integrity in Relation to Frontostriatal and Posterior Cortical Cognitive Performance in Parkinson’s Disease

    Q. Devignes, M. Egan, A. Kayris, S. Peltier, B. Hampstead, L. Hernandez-Garcia (Ann Arbor, USA)

    Objective: Explore relationships of frontostriatal (FS) and posterior cortical (PC) cognitive performance with gray matter (GM) microstructural integrity in Parkinson’s disease (PD). Background: The dual…
  • 2025 International Congress

    Dual task elicited premotor and supplementary motor activity as sensitive markers of mild Parkinson’s disease: an fNIRS analysis

    J. Longhurst, S. Conklin, Y. Chiu (Saint Louis, USA)

    Objective: This study aimed to explore dual-task (DT)-related cortical hemodynamic response (CHR) differences across healthy older adults (HOA), mild Parkinson’s disease (PD), and moderate PD…
  • 2025 International Congress

    Genetic Correlations Between Parkinson’s Disease and Circulating Metabolites

    M. Tan, T. Ascencio, S. Rodriguez-Quiroga, J. Largo González, S. Peña Martinez, L. Hernandez Delgado, A. Noyce (San Salvador, El Salvador)

    Objective: To use genome-wide association studies (GWASs) to identify genetic correlations between Parkinson’s disease (PD) and circulating metabolites. Background: Metabolomics is the study of small…
  • 2025 International Congress

    Prevalence and Characteristics of Glucocerebrosidase Genetic Variants in Nepalese Early-onset Parkinson’s Disease Patients

    R. Ojha, B. Gajurel, N. Gautam, R. Karn, R. Rajbhandari, S. Shahi, V. Sharma, S. Baidya, A. Bhattarai, A. Niraula, E. Tuladhar, A. Adhikari, Y. Tay, S. Lim, A. Tan (Kathmandu, Nepal)

    Objective: To evaluate the genotype and phenotype of early-onset Parkinson´s Disease (EOPD) in the Nepalese population. Background: A significant proportion of early-onset PD (EOPD) can…
  • 2025 International Congress

    Deep phenotyping of Parkinson‘s disease patients with the RAB32 Ser71Arg pathogenic variant and MDSGene literature review

    T. Kleinz, F. Cavallieri, M. Borsche, G. Toschi, F. Valzania, EM. Valente, P. Mitrotti, M. Avenali, S. Zittel, R. Born, M. Matarazzo, C. Shambetova, N. Griebner, L. Santinelli, M. Brand, C. Gabbert, A. Westenberger, J. Trinh, M. Radefeldt, C. Beetz, P. Bauer, N. Brüggemann, C. Klein (Reggio Emilia, Italy)

    Objective: To evaluate patients with PD and unaffected carriers of the pathogenic variant RAB32 p.Ser71Arg using a multimodal approach to gain insight into genotype-phenotype relationships…
  • 2025 International Congress

    Identifying Cut-off Values, Effects of AD Co-pathology, Sex Differences, and Temporal Changes of 123I-FP-CIT SPECT in Autopsy-proven LBD

    T. Miyagawa, S. Przybelski, C. Cynthia, HK. Minmin, L. Forsberg, J. Fields, S. Mccarter, T. Ferman, V. Ramanan, J. Graff-Radford, D. Jones, R. Savica, D. Knopman, R. Petersen, R. Reichard, A. Nguyen, D. Dickson, M. Murray, G. Day, N. Graff-Radford, C. Lachner, E. St Louis, M. Jain, K. Kantarci, V. Lowe, B. Boeve (ROCHESTER, USA)

    Objective: We analyzed autopsy-proven Lewy body disease (LBD) and/or Alzheimer’s disease (AD) dementia patients with 123I-FP-CIT SPECT to investigate previously unclarified detailed aspects of 123I-FP-CIT…
  • 2025 International Congress

    Hispanic Recruitment to PD GENEration at Columbia University

    A. Arroyo, H. Lee, M. Dini, L. Caboy, K. Ghosh Galvelis, R. de Leon, J. Agin-Liebes (New York, USA)

    Objective: To evaluate the effect of having a Hispanic, Spanish-speaking research coordinator on recruitment of Hispanic and Latinx people with Parkinson's disease to the PD…
  • 2025 International Congress

    Profiling Neural Protein Dopaminylation in Parkinson’s disease

    W. Chen, I. Maze (NEW YORK, USA)

    Objective: The hallmark of Parkinson’s Disease is motor dysfunction from the decline in dopaminergic cells in the substantia nigra (SN), leading to the development of…
  • 2025 International Congress

    The efficacy and safety of continuous subcutaneous infusion therapy with foslevodopa/foscarbidopa

    M. Shiraishi, N. Takao, Y. Nakano, Y. Yamano (Kawasaki City, Japan)

    Objective: To clarify the actual status of CSCI therapy, cases in which CSCI therapy was started at our hospital were investigated. Background: Continuous subcutaneous infusion…
  • 2025 International Congress

    The Genetic Landscape of Parkinson’s Disease in African and Admixed Populations: Discovering Population-Specific Risk and Unveiling Etiological Insights

    O. Ojo, N. Okubadejo, M. Makarious, S. Bandres-Ciga (Lagos, Nigeria)

    Objective: To perform the largest PD risk genome-wide association study (GWAS) in the African and African admixed populations. Background: Investigating the genetic foundation of Parkinson’s…
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