Longitudinal shifts in goal-directed and habitual control relate to tic severity and cortico-striatal connectivity in adolescents with Tourette syndrome
Objective: To investigate the balance between goal-directed and habitual control in adolescents with Tourette syndrome (TS) and to determine how longitudinal changes in this balance…Anhedonia in Parkinson’s Disease: Prevalence and Clinical Correlations
Objective: To investigate the prevalence of anhedonia in patients with Parkinson’s disease (PD) and to analyze its relationship with age, motor deficit severity, depression, and…Myoclonic Tremor and Cervical Dystonia as an Atypical Presentation of Ataxia-Telangiectasia
Objective: To describe an unusual case of ataxia-telangiectasia (A-T) presenting with myoclonic tremor and cervical dystonia in the absence of ataxia. Background: A-T is a…Baseline MRI Predictors of Phenoconversion and Prodromal Progression in Non-Manifesting PD Mutation Carriers: A Longitudinal Retrospective Analysis
Objective: We evaluated the sensitivity of baseline MRI measures to predict future PD conversion, and whether baseline MRI associates with MDS prodromal likelihood ratio (LR)…Polypharmacy and its Impact in Individuals with Parkinson’s Disease: Theory- and Data-Driven Approaches
Objective: The aim is to explore the relationship between high prescription drug use (polypharmacy), and its unintended effects on individuals with Parkinson’s Disease (PD). Background:…Caudate-Predominant Striatal Dopaminergic Deficits in bvFTD with Parkinsonism
Objective: To characterize the dopaminergic lesion pattern in behavioral variant frontotemporal dementia with parkinsonism (bvFTD-P) using dopamine transporter (DAT) positron emission tomography (PET), and to…Marked intrafamilial phenotypic variability in VPS13A disease: a case series of three siblings
Objective: To describe a case series of neuroacanthocytosis in three siblings from the same family with the same pathogenic VPS13A nonsense mutation, highlighting the marked…Binge-eating as an Initial Presentation for the Diagnosis of Chorea-acanthocytosis
Objective: - Background: Chorea-acanthocytosis (ChAc) is an autosomal recessive disorder associated with mutations or deletions in the VPS13A gene on chromosome 9q21, which codes for…Quantitative Susceptibility Mapping Revealed Regional Iron Alteration and As a Biomarker for Dopaminergic Deficits in Parkinson’s Disease
Objective: This study aimed to identify regions with altered brain iron accumulation using quantitative susceptibility mapping (QSM) and to investigate the association between iron deposition…Decentralized Clinical Trial of a Phase 3 Light Therapy Device for Parkinson’s Disease: Feasibility, Safety, and Efficacy
Objective: To demonstrate the feasibility of an entirely remote, decentralized clinical trial and evaluate the efficacy and safety of a light therapy device to treat…
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