Non-Motor Outcomes of Unilateral Magnetic Resonance-Guided Focused Ultrasound Surgery in Parkinson’s Disease: A Meta-Analysis
Objective: This study aimed to assess the efficacy of the procedure specifically in relation to non-motor outcomes such as quality of life, disability scores, effect…Cognitive Safety and Stability in DBS for Parkinson’s Disease: Evidence for the Inclusion of Patients with Baseline Mild Cognitive Impairment.
Objective: Investigate the cognitive safety of Deep Brain Stimulation (DBS) in PD patients with baseline pre-operative diagnosis of Mild Cognitive Impairment (MCI) Background: DBS is…Dystonia 3×3: A training framework for beginners in botulinum neurotoxin treatment of cervical dystonia
Objective: To facilitate the education of physicians new to botulinum neurotoxin treatment of cervical dystonia. Background: Cervical dystonia (CD) is a hyperkinetic movement disorder characterized by…Phase 1 Study of BT-267, a potent, selective, brain-penetrant, and oral small molecule inhibitor of LRRK2
Objective: The aim of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of BT-267 in healthy adults. Background: Leucine rich repeat kinase…REM Sleep Behavior Disorder and Clinical Progression in Multiple System Atrophy
Objective: To investigate clinical characteristics of REM sleep behavior disorder (RBD) in multiple system atrophy (MSA) and evaluate associations with disease severity, autonomic dysfunction, and…A Case report of Progressive Supranuclear Palsy with Cerebellar Ataxia and Chorea
Objective: To report a case of progressive supranuclear palsy cerebellar type (PSP-C) with choreiform movements. Background: PSP-C is a rare subtype of PSP characterized by…Efficacy of Vitamin C for Restless Legs Syndrome: A Systematic Review and Meta‑analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy and safety of vitamin C (VITC) for treating restless legs syndrome (RLS) using evidence exclusively from randomized controlled trials (RCTs).…Azathioprine-associated changes in peripheral–central immune signalling in Parkinson’s disease: post-hoc analysis of AZA-PD
Objective: To assess whether changes in peripheral markers of CNS immune cell trafficking relate to clinical response to azathioprine in AZA-PD Background: We conducted a…Digital Kinematic Measures of Finger Tapping Detect Dose-Dependent Effects of Deep Brain Stimulation in Parkinson’s Disease
Objective: To evaluate whether video-based digital kinematic measures can quantify dose-dependent changes in finger tapping performance during deep brain stimulation (DBS) in Parkinson’s disease. Background:…Biomechanical Analysis of Gait Movement Disorders in Spinal Cord Injury and Its Implications for Rehabilitation Strategies
Objective: To systematically analyze the spatiotemporal, kinematic, and electromyographic gait movement disorders in patients with partial SCI for targeted rehabilitation strategies. Background: Spinal cord injury…
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