Influence of Cognitive Function on Obstacle-Crossing Performance in People with Parkinson’s Disease: A Cross-Sectional Study
Objective: This study investigated the influence of cognitive function on obstacle crossing performance in people with Parkinson's disease (PD). Background: Obstacle-crossing is a complex motor…Sleep hygiene practice in patients with Parkinson’s disease
Objective: We examined the prevalence of diverse sleep hygiene behavior and their associations with insomnia severity in PD patients.We examined the prevalence of diverse sleep…Taking the driver’s seat on Parkinson’s care
Objective: To provide insight into the unique service and support offered by the multidisciplinary health team to address the challenges and dilemmas faced by people…Exploring the Effects of Spinal Cord Stimulation for Gait Disturbances in Parkinson’s Disease
Objective: We sought to investigate the effects of SCS in PD, using placebo stimulation, compared to either tonic or burst stimulation paradigms. Background: Gait disturbances…A multiple-dose thorough QT study to evaluate the effect of ampreloxetine on cardiac repolarization in healthy subjects
Objective: To characterize the effect of therapeutic and supratherapeutic doses of ampreloxetine on cardiac repolarization in healthy subjects. Background: Ampreloxetine is a potent NE reuptake…Small Molecule Inhibitors for Precise Inhibition of α-Synuclein Oligomer Generation in Parkinson’s Disease (PD)
Objective: To develop small molecule therapeutics for PD that inhibit production of toxic α-synuclein oligomers and reduce aggregate formation, targeting the molecular mechanisms at the…Comparing the outcome under General Anaesthesia (GA) and Monitored Anesthesia Care (MAC) of Subthalamic Nucleus (STN) – Deep Brain Stimulation (DBS) Surgery for Parkinson’s Disease (PD) in Hong Kong – A single center experience
Objective: To evaluate any difference in the clinical outcome under GA and MAC of STN DBS surgery Background: Traditionally, DBS surgery is performed under MAC…Monocular Ocular Bobbling with Holmes Tremor Due to Ruptured Cavernoma
Objective: To describe a rare and unique manifestation of cavernoma-induced brain injury, specifically the occurrence of monocular ocular bobbing with unilateral Holmes tremor. It aims…Longitudinal changes in brain networks associated with clinical symptoms in idiopathic rapid eye movement sleep behavior disorder
Objective: We aimed to assess changes in brain functional networks and accompanying symptoms over years in patients with idiopathic rapid eye movement sleep behavior disorder…Preoperative trajectory planning is important to minimize intracerebral hemorrhage after deep brain stimulation, in comparison with ventricle peritoneal shunt.
Objective: We compared the occurrence of postoperative intracerebral hemorrhage (ICH) in deep brain stimulation (DBS) and ventricle peritoneal (VP) shunt at our institution. Background: Although…
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