Association of Glymphatic Flow at Diffusion Tensor Image with Motor Symptoms and Striatal Dopamine Degeneration in Parkinson’s Disease
Objective: This study aimed to investigate the association between the diffusion tensor image (DTI) analysis along the perivascular space (ALPS) index, dopamine transporter (DAT) availability…Suicidal Ideation and the Hippocampal Histaminergic System in Huntington’s Disease: A PET Study
Objective: To determine whether presence and severity of suicidal ideation (SI) are associated with hippocampal volume and histamine H3 receptor (H3R) PET uptake in people with Huntington’s disease (PwHD). Background: Suicidal ideation occurs in approximately 8–27% of PwHD, yet its causes remain unclear(1–3). The…Changes in Continuous Good ON and Best ON Time During the Waking Day With Tavapadon in People With Parkinson’s Disease
Objective: To evaluate motor states throughout the waking day when tavapadon is added to oral carbidopa/levodopa in adults with Parkinson’s disease (PD) experiencing motor fluctuations.…Diagnostic Utility of [18F]FDG-PET in the Differential Diagnosis of Parkinsonian Syndromes: A Retrospective Study in an Indian Tertiary Care Cohort
Objective: To evaluate the diagnostic utility of FDG-PET imaging for differentiating Parkinson's disease (PD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal syndrome…Comparative Efficacy of Wrist-Worn Non-Invasive Peripheral Nerve Stimulation for Essential Tremor: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Objective: We aimed to evaluate the efficacy of non-invasive peripheral nerve stimulation (PNS) in reducing clinician-rated tremor severity in essential tremor, assess its effects on…Feasibility and Preliminary Outcomes of an Online Fatigue Self Management Programme for People With Parkinsons Disease
Objective: To assess the feasibility, acceptability, and preliminary outcomes of an online fatigue self management programme for people with Parkinsons disease. Background: Fatigue is a…Perioperative and Longitudinal Outcomes Following Deep Brain Stimulation in Patients with Movement Disorders: A Retrospective Review From a Movement Disorder Program
Objective: To evaluate postoperative symptoms improvement and quality-of-life outcomes in patients with movement disorders following deep brain stimulation (DBS). Background: Deep brain stimulation is an…Skin Tau Quantification as a Potential Degeneration Biomarker in Parkinson’s Disease
Objective: This cross-sectional observational study aims to quantify total skin Tau levels in Parkinson’s disease (PD) patients and explore their association with clinical symptoms. Background:…Quantitative Assessment of Finger Movement Profile in a Visual-Motor Task Using a Tablet Computer: Application in Multiple System Atrophy
Objective: Building on our prior FMAS validation in Parkinson’s disease (PD), we applied this tablet-based system to quantify finger movement in multiple system atrophy (MSA)…Neuropsychiatric Symptoms in Lewy Body Disease: Monoaminergic Activity and Resting State Networks
Objective: Investigating how neuropsychiatric symptoms (NPS)—depression, anxiety, and apathy—relate to functional connectivity between monoaminergic nuclei and the limbic network (LN), default mode network (DMN), and…
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