The Impact of Delaying Subcutaneous Device-Aided Therapy for Patients with Advanced Parkinson’s Disease
Objective: This study aims to evaluate the clinical, humanistic, and societal impact of delayed SC therapy in patients with PD. Background: As Parkinson’s disease (PD)…Sudomotor Dysfunction in Patients With Normal and Abnormal Cardiac MIBG
Objective: We examined the pattern of sweat loss in patients with normal versus abnormal MIBG and considered the implications of this in predicting phenoconversion trajectory.…Oral D1-like/D2-like Receptor Agonist, Lu AF28996, Provides Robust Antiparkinsonian Efficacy with Reduced Dyskinesia in the MPTP-Macaque Model
Objective: Evaluate the therapeutic potential of Lu AF28996 in the MPTP-macaque model of PD. Background: Chronic levodopa treatment is associated with the development of motor…“Shaky Eyes”: an Unusual Case of Ocular Movement Disorder
Objective: To report an unusual video case of paroxysmal conjugate saccadic ocular oscillations and discuss the challenges in the diagnostic process differentiating ocular movement disorders.…A Novel Clinical Protocol for Monitoring Therapeutic Outcomes in Camptocormia in Parkinson´s Disease
Objective: To present a case study using a novel protocol evaluating postural, pain, and respiratory outcome in PD-related camptocormia before and after treatment. Background: Camptocormia…Parkinson’s Disease Early Diagnostic and Prognostic Biomarkers Identified by Large-scale Plasma and Cerebrospinal Fluid Proteomic Profiling
Objective: To identify reliable diagnostic and prognostic protein biomarkers for early-stage Parkinson’s disease (PD) using large-scale proteomic profiling of plasma and cerebrospinal fluid (CSF).To identify…Nutritional Assessment in X-linked Dystonia Parkinsonism: Preliminary Results from a Pilot Study
Objective: This pilot study aims to evaluate the nutritional status of XDP patients using anthropometric measurements and nutritional assessment tools, and to determine the prevalence…Levodopa-Responsive Dystonia in Adenylosuccinate Lyase (ADSL) Deficiency Treated With Bilateral GPi Deep Brain Stimulation
Objective: To describe levodopa-responsive dystonia in ADSL deficiency and the use of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for refractory symptoms. Background:…Digital Health, Telemedicine, and Artificial Intelligence in Parkinson’s Disease Management During COVID-19: A Narrative Review
Objective: The objective of this narrative review was to evaluate the effectiveness of telemedicine and AI-based technologies used for the remote monitoring and management of…Effectiveness and Safety of Deutetrabenazine in Chinese Patients with Huntington’s Disease-associated Chorea: A Multicenter Phase 4 Study
Objective: To evaluate the effectiveness and safety of deutetrabenazine (DTBZ) in Chinese patients with Huntington’s Disease (HD)-associated chorea. Background: Chorea is a key symptom of…
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