Outcomes of Focused Ultrasound Thalamotomy in Tremor Syndromes
Objective: To report on the outcomes between tremor subtypes, Essential Tremor (ET), Dystonic Tremor (DT) and Parkinson Disease Tremor (PDT), following a unilateral Magnetic Resonance…Plasma biomarkers in iRBD patients serve as potential markers of early PD and motor severity
Objective: We aimed to investigate biomarkers of inflammation and neuroaxonal damage in people with isolated REM sleep behaviour disorder (iRBD) compared to controls, and understand…Analysis of α-Synuclein Seed Amplification Assay in Carriers of GBA and LRRK2 Pathogenic Variants
Objective: To assess α-synuclein seed amplification assay (αS-SAA) in cerebrospinal fluid (CSF) from a cohort of PD patients and non-manifesting carriers (NMCs) of pathogenic GBA…Clinical implication of small vessel disease burden on deep brain stimulation outcome in Parkinson’s disease
Objective: We aimed to investigate the correlation between the small vessel disease (SVD) burden and the 1-year outcome after the globus pallidus interna (GPi) deep…Identification of ZYIL1, a novel NLR family pyrin domain containing 3 protein inhibitor: a potential disease modifier in Parkinson’s disorder
Objective: Identification and evaluation of the potential of a novel NLR family pyrin domain containing 3 (NLRP3) inflammasome inhibitor (ZYIL1) as a Parkinson’s disease (PD)…Cholinergic topography and clinical profile of early Parkinson’s patients with GBA mutations
Objective: To explore the regional cholinergic innervation and clinical profile of early Parkinson’s disease (PD) patients carrying GBA mutations (GBA-PD). Background: The most common genetic…Characterisation of OFF-Time in Levodopa-Treated Parkinson’s Patients: A Post-hoc Analysis of an Exploratory Trial
Objective: This analysis aims to study the evolution of OFF and ON patterns during a 12-hour daily period in patients with Parkinson’s disease (PD) and…Influence of square-stepping exercise on brain activation in older adults with cognitive frailty
Objective: To investigate the brain activity induced by square-stepping exercise (SSE), as well as the relationships between brain activity change and SSE performance in older…Neuroimaging correlates of postural instability in motor subtypes of Parkinson’s disease
Objective: In this study, we aimed to identify the brain structures associated with postural instability (PI) in Parkinson’s disease (PD) subtypes using different MRI approaches. Background:…Impact of endpoint selection on sample size calculations for disease-modifying clinical trials in Parkinson’s disease patients with GBA1 mutations
Objective: To assess clinical trial sample size estimations under variable simulated scenarios for Parkinson’s disease (PD) patients with mutations in the β-glucocerebrosidade gene (GBA1). Background:…
- « Previous Page
- 1
- …
- 242
- 243
- 244
- 245
- 246
- …
- 1554
- Next Page »