Therapeutic Efficacy of Human Dental Pulp Stem Cells-Derived Exosome-Encased Phloroglucinol In MPTP-Induced Chronic Parkinsonian Rat model: Potential for Disease Modification
Objective: This study aimed to evaluate the therapeutic efficacy of intranasally administered exosome-encased phloroglucinol (Exo-Phl) in a MPTP rat model of PD. Background: Dopaminergic (DA)…White Matter and Subcortical Alterations in Focal Dystonia: A MRI Study of Subtype-Specific Brain Changes
Objective: To assess structural brain alterations in patients with cervical dystonia (CD) and focal upper limb dystonia (ULD) relative to healthy controls, using MRI exploratory…The Benefits of Whole-Body Electro Muscle Stimulation (WB-EMS) in a patient with Parkinson’s Disease
Objective: To determine the motor and non-motor benefits of WB-EMS in a patient with Parkinson’s disease Background: Parkinson’s disease causes both motor and non-motor symptoms.…Screening for Neuronal Synuclein Disease (NSD) using cerebrospinal fluid (CSF) in the Parkinson Progression Marker Initiative (PPMI)
Objective: To utilize a centralized screening paradigm for early stage NSD based on sequential olfactory dysfunction (measured by University of Pennsylvania Smell Identification test (UPSIT))…Physiotherapy for Dystonia in the UK: Current Practice, Patient Perspectives, and Future Directions
Objective: To determine the proportion of patients with dystonia accessing physiotherapy services in the United Kingdom, identify potential barriers to access, and gather patient perspectives…Anti-Diabetic Medications to Fight Parkinson’s Disease and Lewy Body Dementia
Objective: To evaluate the tolerability and clinical effects of newer antidiabetic drugs in individuals with Parkinson's disease (PD) and Lewy body dementia (LBD). Background: Parkinson’s…Honey products in Parkinson’s disease – randomized placebo-controlled double-blind pilot study
Objective: The purpose of this study is to examine whether consumption of honey products can improve symptoms and their diurnal fluctuations in patients with Parkinson's…Risk of Motor Complications in Early Parkinson’s Disease Patients Treated with Opicapone in the EPSILON study: Effect of Levodopa Dose
Objective: This post-hoc analysis of the EPSILON study evaluated whether levodopa dose (<400mg/day vs. ≥400mg/day) and opicapone (OPC) timing (at double-blind [DB] or open-label extension…Phenotypic, Genotypic, Imaging and Neuropsychological Profile of Friedreich Ataxia
Objective: 1. To characterise the phenotypic and genotypic spectrum of patients with Friedreich Ataxia2. To describe the imaging findings and to assess the neuropsychological profile…Clinical and Genetic spectrum of Developmental dyskinetic encephalopathy – Experience from a Tertiary care centre
Objective: To provide unique data on the clinical and genetic spectrum of developmental dyskinetic encephalopathies. Background: Developmental dyskinetic encephalopathy(DDE) is a recently described clinically and…
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