Cerebrospinal fluid DOPA decarboxylase levels as a marker of disease severity in Parkinson’s Disease
Objective: To assess the correlation of CSF DDC levels to DaT-SPECT SBR in PD and iRBD. Background: Raised cerebrospinal fluid (CSF) proteomic biomarker, DOPA decarboxylase…Efficacy and Safety of Different Apomorphine Formulations for OFF Episodes in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the efficacy and safety of different apomorphine formulations for managing OFF episodes in Parkinson’s disease (PD) through a systematic review and meta-analysis.…Scopolamine-induced Tardive Dyskinesia: A Case Report
Objective: To present a case of scopolamine-related Tardive Dyskinesia (TD) and review the documented anticholinergic-associated cases of TD and the underlying pathophysiology responsible for TD.…Randomized Trial comparing Directional DBS with Ring-mode DBS in PD
Objective: To evaluate whether directional DBS is more effective in reducing PD motor symptoms and causes fewer stimulation-induced adverse effects (AE) than ring-mode DBS. Background:…Evaluation of Local Field Potential-guided DBS-programming in a Parkinson’s disease outpatient clinic
Objective: To evaluate potential use and applicability of local field potential-guided DBS-programming under real-life conditions in a Parkinson’s disease (PD) outpatient clinic. Background: Deep brain…Lingual tremor secondary to ischemic stroke of the left middle cerebral artery: Another movement disorder with cortical localization?
Objective: Lingual tremor is an uncommon movement disorder, occasionally reported secondary to cortical strokes. We present a patient diagnosed with an ischemic stroke of the…Wearable-based digital measures from the Verily Study Watch can detect concurrent symptomatic treatment effects in a subset of early-stage Parkinson’s disease ORCHESTRA trial participants
Objective: To investigate the effect of concurrent symptomatic treatment (ST) on digital measures collected in ORCHESTRA (NCT04658186). Background: Minzasolmin is an oral small molecule that…Tumeric and Curcumin Improve Motor Function and Reduce Catalepsy in a Rotenone -Induced Parkinson’s Disease Model
Objective: Catalepsy measurements play a crucial role in behavioral research on Parkinson’s disease (PD), as they reflect significant motor impairments associated with dopaminergic dysfunction. In…Limb Myorhythmia in a Patient With Anti-LGI-1 Encephalitis
Objective: N/a Background: Myorhythmia is a hyperkinetic involuntary movement disorder characterized by slow rhythmic movements (1-4 Hz), typically affecting cranial and/or limb muscles. Recognizing the…Functional and Biomechanical characterization through the progression of Parkinson’s Disease
Objective: To describe clinical, electromyographic, and gait kinematic parameters throughout Parkinson’s disease (PD) progression Background: PD is the second most prevalent neurodegenerative disease worldwide. Classic…
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