Enhancement of deep sleep in people with Parkinson disease using auditory stimulation of slow waves at home
Objective: To test the feasibility and effectivity of a new method for non-pharmacological enhancement of deep sleep in Parkinson disease (PD). Background: Sleep-wake disturbances and…6-[18F]fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET striatal binding patterns in patients with Parkinson’s Disease and Parkinson Plus Syndromes.
Objective: In this study we investigate striatal binding patterns in patients with Idiopathic Parkinson’s disease (IPD), compared to those with Parkinson Plus syndromes (PPS) versus…Feasibility and acceptability of implementing dignity therapy as a supportive intervention for people with movement disorders.
Objective: To determine the feasibility and acceptability of implementing Dignity Therapy (DT) in a neuropalliative clinic, and to determine preliminary efficacy. Background: Awareness of the…Taking the driver’s seat on Parkinson’s care
Objective: To provide insight into the unique service and support offered by the multidisciplinary health team to address the challenges and dilemmas faced by people…Sleep hygiene practice in patients with Parkinson’s disease
Objective: We examined the prevalence of diverse sleep hygiene behavior and their associations with insomnia severity in PD patients.We examined the prevalence of diverse sleep…A 78-year-old man with progressive ataxia, palatal tremor, parkinsonism and motor neuron disease.
Objective: To report a unique case of palatal tremor associated with parkinsonism, ataxia and motor neuron disease. Background: Progressive ataxia with palatal tremor (PAPT) is…A novel truncating variant in UBAP1 gene causing hereditary spastic paraplegia type 80
Objective: To describe a novel truncating variant in UBAP1 gene in a first Malay population, and expand the genotype and phenotype. Background: Hereditary Spastic paraplegia…Investigating Digital Biomarkers in Parkinson’s Disease
Objective: Our objective is to investigate potential digital biomarkers of Parkinson’s Disease (PD) for early diagnosis and treatment. Background: Parkinson’s disease presents difficulty with early…A 16-week open-label study of the effects of treatment with pimavanserin on activities of daily living in subjects with Parkinson’s disease psychosis (PDP)
Objective: To examine the effects of pimavanserin on activities of daily living during treatment for Parkinson’s Disease psychosis. Background: Accurate assessment of disability associated with…Obesity is a protective factor for the development of Parkinson’s disease in participants of the Framingham Heart Study Cohort
Objective: To determine the role of obesity in the development of Parkinson's disease in a retrospective matched cohort study. Background: Parkinson’s disease (PD) is a…
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