Hesperidin ameliorates rotenone-induced Parkinson’s disease in mice via improving neuroinflammation and oxidative stress
Objective: The goal of the present study is to examine the neuroprotective property of hesperidin on rotenone-induced Parkinson's disease in mice. Background: The second most…Treatment induced psychogenic movement disorders: a case series
Objective: To describe new onset psychogenic movement disorders in 2 patients who underwent Deep Brain Stimulation (DBS) for Parkinson’s disease (PD) and MR guided Focused…NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease.
Objective: To determine the safety of oral nicotinamide riboside (NR) 3000 mg daily for 4 weeks in Parkinson’s disease (PD). Secondary objectives: To assess NRs…Cognitive flexibility associates with atrophy and disrupted connectivity of the cognitive cerebellum in degenerative cerebellar ataxia
Objective: This study was to investigate the features of cognitive flexibility in patients with degenerative cerebellar ataxia, and to identify the pathophysiological correlates of cognitive…Population-Scale Long-Read Sequencing to Catalog Structural Variants in Parkinson’s Disease
Objective: We aimed to generate a population scale long-read sequencing dataset to begin to catalog structural variants in Parkinson’s disease (PD) to identify potential new variants…Fluorescence-lifetime ophthalmoscopy findings in Parkinson’s disease patients with visual disturbances
Objective: We identified fluorescence-lifetime ophthalmoscopy changes in Parkinson’s disease (PD) patients experiencing visual disturbances. Background: Fluorescence-lifetime ophthalmoscopy (FLIO), a novel in vivo imaging method generating…restless leg syndrome in parkinson’s disease patients: prevalence and correlates with sleep parameters
Objective: The aim of the present study is to explore the clinical significance and frequency of restless leg syndrome (RLS) in a sample of patients…The role of structural changes in the retina and the vertical vestibulo-ocular reflex abnormality in gait disorders in Parkinson`s disease
Objective: Our goal was to investigate retinal structural changes as well as changes in visual cortex in PD patients with suppression deficiency of VOR and…Validation of the EQ-5D-3L in Spinocerebellar Ataxia (SCA)
Objective: Our study aims to assess the acceptability, validity and responsiveness of the EQ-5D-3L in SCA types 1, 2, 3 and 6. Background: Although health-related…London-Dhaka Parkinson’s Cognition Study: A collaboration to evaluate cognitive impairment in under-represented Parkinson’s disease patients
Objective: Our aim is to study the prevalence of cognitive impairment (CI) in a diverse group of people with Parkinson's disease (PwP) from East London,…
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