MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2023 International Congress

    Design of a time-to-event study in GBA Parkinson’s Disease patients: Efficacy and safety of BIA 28-6156, an allosteric activator of beta-glucocerobridase (GCase)

    L. Magalhães, M. Fonseca, G. Castilla-Fernández, R. Costa, D. Simon, J. Holenz, N. Mendonça (Coronado, Portugal)

    Objective: To assess the efficacy of BIA 28-6156 in delaying clinically meaningful motor progression in PD patients who have a PD-risk associated variant in the…
  • 2023 International Congress

    Dry Cleaning Chemicals and Parkinson’s Disease

    M. Pawlik, S. Lettenberger, M. Zafar, P. Auinger, K. Hylton, M. Coffey, S. Goldman, B. de Miranda, K. Kieburtz, H. Schwarz, R. Barbano, M. Braun, J. Adams, D. Kinel, R. Dorsey (Rochester, USA)

    Objective: To characterize health outcomes of attorneys potentially exposed to dry cleaning chemicals. Background: Trichloroethylene (TCE), a chlorinated solvent used in dry cleaning and degreasing,…
  • 2023 International Congress

    Open-label Extension Study of Long-term Safety and Tolerability of Foslevodopa/Foscarbidopa for Treatment of Advanced Parkinson’s Disease

    V. Fung, J. Aldred, F. Bergquist, E. Danielsen, A. Jeong, J. Jia, A. Spiegel, S. Talapala, C. Carroll (Westmead, Australia)

    Objective: To evaluate long-term safety/tolerability of foslevodopa/foscarbidopa (LDP/CDP) in patients with advanced Parkinson’s disease (aPD) in a phase 3 open-label extension (OLE) study. Background: LDP/CDP…
  • 2023 International Congress

    Non classified SCA-like presentation of GEMIN5 + GYG-1 mutation. Case report

    A. Escalante Mercado, G. Calderon Paiva, J. Medina Suárez, P. Gonzales Romero, W. Trillo Alvarez, J. Calderon Paiva, P. Bermejo Rosado, A. Aquino Toledo, L. Chavez Torreblanca (Arequipa, Peru)

    Objective: To report the first case of a patient with GEMIN5 and GYG-1 genes mutations who presented with features of both SCA and myopathy. Background:…
  • 2023 International Congress

    Adult hippocampal neurogenesis-associated memory performance in people with Parkinson’s disease with and without cognitive impairment

    L. Batzu, A. Podlewska, J. Staunton, P. Tall, V. Leta, C. Kim, S. Thuret, K. Ray Chaudhuri (London, United Kingdom)

    Objective: To evaluate the role of adult hippocampal neurogenesis (AHN)-associated memory measures to the cognitive performance of people with Parkinson’s disease (PwP) with or without…
  • 2023 International Congress

    The impact on religiosity following Deep Brain Stimulation (DBS) in patients with Essential Tremor (ET) and Parkinson’s Disease (PD)

    J. Frey, J. Lobo Lopes, M. Wajid, L. Kugler, C. Hess (Morgantown, USA)

    Objective: To determine the impact of DBS on religiosity. Background: Religiosity has been mapped to various brain networks1, 2, and transcranial magnetic stimulation has transiently…
  • 2023 International Congress

    Directional deep brain stimulation therapy in the long term

    E. Sanesteban Beceiro, A. Fernández Revuelta, E. López Valdés, R. García-Ramos, C. Fernández García, F. Alonso Frech (Madrid, Spain)

    Objective: To describe our long-term clinical experience with directional deep brain stimulation (d-DBS) in patients with advanced Parkinson’s disease (PD) who have been implanted with…
  • 2023 International Congress

    Effects of Boxing and conventional physiotherapy techniques in patients with PD: A randomized control study

    W. Kamel, M. Asala, A. Al-Tajalli, A. Al-Tammar, R. Alkhaldi, C. Ramos Jr, A. Mubarak (beni suef, Egypt)

    Objective: To determine the effectiveness of boxing vs. conventional physiotherapy techniques in improving the quality of movement, motor, cognitive functions in patients with PD. Background:…
  • 2023 International Congress

    Axial tremor response to tractography-defined focused ultrasound thalamotomy for essential tremor: a prospective study

    C. Ribacoba Díaz, A. Fernández Revuelta, M. Yus Fuertes, C. Pérez García, E. López Valdés, R. García Ramos (Madrid, Spain)

    Objective: To analyse the effects of unilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy defined by 4-tract tractography on axial tremor at 6 months in patients…
  • 2023 International Congress

    Worsening of Essential Tremor after SARS-CoV-2 infection: 1 year follow up.

    D. Costa, L. Angelini, M. Passaretti, D. Birreci, D. Colella, A. Cannavacciuolo, G. Paparella, A. Berardelli, M. Bologna (Rome, Italy)

    Objective: To follow up on clinical and kinematic tremor features as well as non-motor symptoms, neuroimaging, and laboratory changes in a patient diagnosed with essential…
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