Design of a time-to-event study in GBA Parkinson’s Disease patients: Efficacy and safety of BIA 28-6156, an allosteric activator of beta-glucocerobridase (GCase)
Objective: To assess the efficacy of BIA 28-6156 in delaying clinically meaningful motor progression in PD patients who have a PD-risk associated variant in the…Dry Cleaning Chemicals and Parkinson’s Disease
Objective: To characterize health outcomes of attorneys potentially exposed to dry cleaning chemicals. Background: Trichloroethylene (TCE), a chlorinated solvent used in dry cleaning and degreasing,…Open-label Extension Study of Long-term Safety and Tolerability of Foslevodopa/Foscarbidopa for Treatment of Advanced Parkinson’s Disease
Objective: To evaluate long-term safety/tolerability of foslevodopa/foscarbidopa (LDP/CDP) in patients with advanced Parkinson’s disease (aPD) in a phase 3 open-label extension (OLE) study. Background: LDP/CDP…Non classified SCA-like presentation of GEMIN5 + GYG-1 mutation. Case report
Objective: To report the first case of a patient with GEMIN5 and GYG-1 genes mutations who presented with features of both SCA and myopathy. Background:…Adult hippocampal neurogenesis-associated memory performance in people with Parkinson’s disease with and without cognitive impairment
Objective: To evaluate the role of adult hippocampal neurogenesis (AHN)-associated memory measures to the cognitive performance of people with Parkinson’s disease (PwP) with or without…The impact on religiosity following Deep Brain Stimulation (DBS) in patients with Essential Tremor (ET) and Parkinson’s Disease (PD)
Objective: To determine the impact of DBS on religiosity. Background: Religiosity has been mapped to various brain networks1, 2, and transcranial magnetic stimulation has transiently…Directional deep brain stimulation therapy in the long term
Objective: To describe our long-term clinical experience with directional deep brain stimulation (d-DBS) in patients with advanced Parkinson’s disease (PD) who have been implanted with…Effects of Boxing and conventional physiotherapy techniques in patients with PD: A randomized control study
Objective: To determine the effectiveness of boxing vs. conventional physiotherapy techniques in improving the quality of movement, motor, cognitive functions in patients with PD. Background:…Axial tremor response to tractography-defined focused ultrasound thalamotomy for essential tremor: a prospective study
Objective: To analyse the effects of unilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy defined by 4-tract tractography on axial tremor at 6 months in patients…Worsening of Essential Tremor after SARS-CoV-2 infection: 1 year follow up.
Objective: To follow up on clinical and kinematic tremor features as well as non-motor symptoms, neuroimaging, and laboratory changes in a patient diagnosed with essential…
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