Intermuscular coherence as a biomarker of subthalamic nucleus deep brain stimulation efficacy in Parkinson’s disease
Objective: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an established treatment in advanced Parkinson’s disease (PD). However, the clinical outcome after STN-DBS is…Sisters with a novel compound heterozygous mutation in GCH1 gene linked to dopa responsive dystonia
Objective: Objective: Two sisters with a diagnosis of dopa-responsive dystonia (DRD) with a new mutation are reported. Background: Background: GTP cyclohydrolase I (GCH1) mutations are…The effect of short-term treadmill exercise in the alpha-synuclein preformed fibril rat model of Parkinson’s disease
Objective: To determine how treadmill exercise impacts behavior and Parkinson-related pathology in the alpha-synuclein (a-syn) preformed fibril (PFF) model. Background: Exercise is often recommended by…Prepulse inhibition of the blink reflex in functional movement disorders
Objective: To assess the influence of directed attention on prepulse inhibition (PPI) of the blink reflex in patients with functional movement disorders (FMD) and healthy…Patient Advisory Boards: A Model for Patient Engagement in Parkinson’s Disease Comparative Effectiveness Research
Objective: To build a replicable, sustainable model of patient engagement in Parkinson’s disease (PD) comparative effectiveness research (CER) at academic research centers through patient advisory…Initial Postmarketing Real World Experience with directSTIM™ DBS System: A Case Series
Objective: In this study we report the first three cases of a new, CE-marked system for deep brain stimulation. Background: The PMCF study is a…Liraglutide once daily versus placebo in Parkinson’s disease: a randomized, double-blind, placebo-controlled trial
Objective: To test safety and efficacy of the glucagon-like peptide 1 (GLP-1) agonist liraglutide in idiopathic Parkinson’s disease (PD). Background: Insulin resistance (IR) may play…Diagnosed and Drug-Treated Prevalence of Essential Tremor in Pediatric Patients: Retrospective Analyses of Two US Healthcare Claims Databases
Objective: Estimate the prevalence of diagnosed and drug-treated essential tremor (ET) in the pediatric population using 2 US healthcare claims databases. Background: An ET diagnosis…Effects of a novel neurotrophic compound in an animal model of Parkinson’s disease
Objective: Investigate the neuroprotective effect of a novel compound in an animal model of Parkinson’s disease. Background: Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived…Boostering motor imagery processing to improve gait in patients with Parkinson disease and freezing of gait: a preliminary study
Objective: The aim of this study is to evaluate the priming effect of visual, auditory and cognitive tasks in enhancing Motor Imagery (MI) ability in…
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