The role of genetic factors in the occurrence of levodopa-induced motor complications in Parkinson’s disease
Objective: We aimed to evaluate the association of selected polymorphisms of COMT, DRD2, ANKK1, and DAT genes and the occurrence of levodopa-induced motor complications in…A Parkinson Shoe with Combined Plantar Pressure and Vibratory Stimulation in Parkinson’s Disease Patients with Freezing of Gait: A Randomized Controlled Trial with Plantar Pressure Analysis
Objective: To explore the effect of PD shoes on plantar pressure in PD patients with FOG. Background: Dysfunction of peripheral sensory systems, including decreased cutaneous mechanoreceptors…Distinct deep grey matter iron accumulation in tremoric syndromes; an apparent quantitative susceptibility mapping mangetic resonance study
Objective: To investigate regional iron accumulation in patients with essential tremor (ET) and Parkinson´s disease (PD) and its clinical associations with apparent susceptibility-weighted imaging (SWI)…Peripheral Synucleinopathy in Essential Tremor Plus Patients with Parkinsonian Features and Normal Dopamine Transporter Imaging
Objective: To describe results of skin biopsy for phosphorylated alpha-synuclein (P-SYN) in patients with essential tremor (ET) with parkinsonism. Background: Patients with longstanding ET may…A pilot study to prepare patients for doctor’s consultation based on the NMS-Quest and a wearable medical device
Objective: To evaluate the feasibility of a consultation preparation service (CPS) for Parkinson's Disease patients and its effect on the patients’ experience during consultation. Background:…Diagnostic Utility of Blood α-Synuclein in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: The aims were to (1) explore the concentration differences of α-syn species in different blood components between PD and healthy controls (HC), and between…The prevalence and characteristics of REM sleep behavior disorder in progressive supranuclear palsy patients.
Objective: To describe the prevalence and characteristics of RBD in patients diagnosed with PSP and to demonstrate the association with each PSP subtype. Background: Rapid…Membrane-associated properties and ER stress alterations in LRRK2 I1371V patient iPSC derived neurons increase susceptibility to oxidative stress.
Objective: To evaluate the pathophysiology of the midbrain dopaminergic neurons (mDAN) derived from LRRK2 I1371V PD patient-iPSCs leading to susceptibility to oxidative stress. Background: Studies…Pain in people with multiple system atrophy
Objective: To estimate prevalence of pain in people with multiple system atrophy (MSA).To estimate prevalence of pain in people with multiple system atrophy (MSA). Background:…Modeling Parkinson’s disease progression accounting for the effect of symptomatic treatments in the Parkinson’s Progression Markers Initiative study
Objective: To explore the natural history of Parkinson’s disease (PD) accounting for the effect of symptomatic treatments on progression by modeling the time course of…
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