Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease
Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…Visualising cholinergic nerves in dementia with Lewy bodies using PET and FEOBV
Objective: Investigate the cholinergic integrity of the central nervous system in dementia with Lewy bodies using PET and a tracer for the vesicular acetylcholine transporter.…Can abdominal internal oblique muscle be a possible target for ultrasound-guided Botulinum toxin injection in patients with Parkinson’s Disease affected by axials problems? An ultrasound study of our case series.
Objective: to demostrate the abdominal internal oblique muscle hypertrophy with ultrasound in patients with Parkinson’s Disease (PD) affected by axial problems, as a possible target…Task Specific Oromandibular dystonia due to Shisha (Hookah) Smoking- “Shisha Dystonia”
Objective: To report an unusual case of oromandibular dystonia due to repeated task of smoking shisha/hookah. Background: Focal task-specific dystonia is common in men, aged…GDNF Gene Therapy for Parkinson’s Disease (PD): Preliminary Safety and Clinical Findings from a Phase Ib Study
Objective: Assess the safety and tolerability of intraputaminal AAV2-GDNF in mild to moderate PD Background: Glial cell line-derived neurotrophic factor (GDNF) is critical for dopaminergic…Effects of Parkinson’s disease and freezing of gait on the kinematic and kinetic gait parameters
Objective: This study aims to evaluate the effects of Parkinson's disease and freezing of gait (FoG) on the kinematic and kinetic gait parameters, both in…Heart rate variability is affected by standing and medication intake in Parkinson’s disease
Objective: To evaluate the effect of levodopa and orthostatism on heart rate variability (HRV) in a sample of consecutive subjects with Parkinson's disease (PD). Background:…The effect of levodopa on speech in patients with Parkinson’s disease
Objective: To assess levodopa-induced changes in fMRI signal in areas involved in speech production (ROIs) in PD. Evaluate association between these changes and changes in…The effect of Deep Brain Stimulation on Sense of agency in Parkinson’s disease patients with and without impulsive compulsive behaviours.
Objective: To evaluate the effect of Deep Brain stimulation of the Subthalamic Nucleus (STN-DBS) on sense of agency in PD patients undergoing DBS; To look…A second level neuropsychological battery for Parkinson’s Disease. Normative data from the Italian population.
Objective: The main purpose of this work is to propose modern Italian co-normed data for a battery of ten widely used neuropsychological tests for Parkinsons’…
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