Qihuang Needle Therapy for Motor Symptoms in Parkinson’s Disease: A Randomized Controlled Trial
Objective: To evaluate the efficacy of Qihuang needle therapy for improving motor and non-motor symptoms in patients with Parkinson’s disease (PD). Background: Motor symptoms in…Survival and Related Factors in Patients with Parkinson’s Disease : A Multicenter Prospective Cohort Study in China
Objective: To estimate mortality, standardized mortality ratios (SMRs), causes of death, and survival-related risk factors in a large, multicenter Parkinson’s disease (PD) cohort from the…In Vivo 18F-Florzolotau Tau PET Imaging in Parkinson’s Disease with and without Probable REM Sleep Behavior Disorder
Objective: To investigate the distribution and potential influence of tau pathology in Parkinson’s disease (PD) patients with and without prodromal REM sleep behavior disorder (pRBD),…Changes in Continuous Good ON and Best ON Time During the Waking Day With Tavapadon in People With Parkinson’s Disease
Objective: To evaluate motor states throughout the waking day when tavapadon is added to oral carbidopa/levodopa in adults with Parkinson’s disease (PD) experiencing motor fluctuations.…Early Clinical Characteristics of Pathologically Confirmed Progressive Supranuclear Palsy and Corticobasal Degeneration
Objective: This study aimed to characterize the early clinical features of PSP and CBD to inform clinicians on diagnostic assessment and management strategies. Background: Although…Comparative efficacy and safety of Safinamide versus Opicapone in Japanese patients with Parkinson’s Disease and wearing-off: A matching-adjusted indirect comparison
Objective: To compare efficacy and safety outcomes with safinamide and opicapone as adjuncts to levodopa in Parkinson’s disease (PD) patients with wearing-off using an anchored…Suicidal Ideation and the Hippocampal Histaminergic System in Huntington’s Disease: A PET Study
Objective: To determine whether presence and severity of suicidal ideation (SI) are associated with hippocampal volume and histamine H3 receptor (H3R) PET uptake in people with Huntington’s disease (PwHD). Background: Suicidal ideation occurs in approximately 8–27% of PwHD, yet its causes remain unclear(1–3). The…Integrating Multidisciplinary, Family-Centered Care to Optimize Functional Outcomes in Children with Cerebral Palsy.
Objective: Optimal management of Cerebral Palsy requires coordinated, evidence-based interventions that address both motor and non-motor domains across the lifespan. Background: Randomized controlled trials (RCTs)…Association of Glymphatic Flow at Diffusion Tensor Image with Motor Symptoms and Striatal Dopamine Degeneration in Parkinson’s Disease
Objective: This study aimed to investigate the association between the diffusion tensor image (DTI) analysis along the perivascular space (ALPS) index, dopamine transporter (DAT) availability…Linear-Time RWKV Multimodal Fusion of Smartphone Audio and Wearable Signals for Mild Cognitive Impairment Screening
Objective: To evaluate linear-time RWKV-based multimodal fusion for classifying mild cognitive impairment (MCI) from synchronized smartphone audio and consumer wearable signals, and to compare alternative…
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