Unique consecutive order of brain atrophy in spinocerebellar ataxia type 3 (SCA3)
Objective: The aim was to identify the sequence of brain regions becoming atrophic in the early phase of spinocerebellar ataxia type 3 (SCA3). Background: SCA3…Pain and sleep in Parkinson’s disease
Objective: Pain and sleep disturbances are among the most frequently encountered non-motor symptoms in Parkinson’s disease (PD). Background: The aim of this study was to…The effect of subthalamic therapeutic deep brain stimulation on pallidal and cortical activity in Parkinson’s disease
Objective: To evaluate the effect of subthalamic (STN) deep brain stimulation (DBS) on the globus pallidus (GP) and motor cortex Background: Progressive neuronal loss in…Identification of xylopropamine as a potential dopamine D2 receptor agonist through computational drug discovery pipeline
Objective: This study aims to identify novel dopamine D2 receptor agonists through the computational drug discovery pipeline. Background: Parkinson's disease (PD) is a neurodegenerative disorder…The Prevalence of Primary Tauopathies in Ireland; a Clinically-Defined Study in the Province of Leinster: design and initial data.
Objective: To investigate the epidemiology and phenomenology of PSP and CBS within the province of Leinster. Background: PSP and CBS are uncommon parkinsonian disorders. Studies…Cognitive overlap between Parkinson disease (PD) and Alzheimer’s disease (AD) is associated with plasma biomarkers and their impact on regional cortical thickness (CT): An ONDRI Study
Objective: To investigate cognitive performance across the Parkinson-Alzheimer’s spectrum and its association with plasma biomarkers and regional CT. Background: While PD and AD are neurodegenerative…Neuroimaging and correlation with functional status in children with cerebral palsy
Objective: To analyse the neuroimaging findings and to establish a correlation between clinical features and magnetic resonance imaging (MRI) patterns in children with cerebral palsy…At-home adaptive deep brain stimulation improves motor fluctuations and quality of life in patients with Parkinson’s disease: a single-blind randomized study
Objective: We evaluated the effect of at-home adaptive deep brain stimulation (aDBS) based on personalized neural biomarkers on motor symptoms and quality of life (QoL)…Deep Brain Stimulation Duration and Changes in Basal Ganglia Excitatory/Inhibitory Balance in Children and Young Adults with Dystonia
Objective: We sought to explore associations between basal ganglia aperiodic signals and time since deep brain stimulation (DBS) implantation in children and young adults with…Electrophysiological evaluation of brainstem function in patients with idiopathic normal pressure hydrocephalus
Objective: To explore the brainstem function in patients with idiopathic normal pressure hydrocephalus (iNPH) by means of a multimodal electrophysiological assessment of trigeminal, facial, and…
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