Cognitive Interference in Postural Control as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders.
Objective: The purpose of this research is to explore whether Progressive supranuclear palsy (PSP) patients display distinct sway patterns compared to idiopathic Parkinson's disease (PD)…Supra-ON state freezing of gait: The unpredictable response to levodopa in Parkinson´s Disease
Objective: To discuss the therapeutic dilemma of freezing in supra ON Background: Freezing of gait (FOG) is a common manifestation of Parkinson's disease (PD), occurring…Recommendations to tackle under-recognition and under-treatment of sialorrhea in Parkinson’s Disease: Is it time for a paradigm shift?
Objective: To leverage patient survey data and expert opinion to develop recommendations for managing sialorrhea in patients with Parkinson’s disease (PD). Background: Sialorrhea, or drooling,…Predicting ALS progression using remote sensor-based assessments
Objective: To develop a predictive model of amyotrophic lateral sclerosis (ALS) progression using self-administered digital assessments. Background: Remote fit-for-purpose sensor-based assessments stand to enhance the…Depression in Parkinson’s disease is associated with subcortical neurodegeneration and increased risk of all-cause mortality and dementia
Objective: To evaluate the temporality, neuroanatomical correlates and prognostic significance of depression in PD using a large population cohort. Background: Depression may be an important…Effects of cerebellar theta burst stimulation on working memory in Parkinson’s disease
Objective: This study aims to investigate the effects of cerebellar theta burst stimulation (TBS) on working memory (WM) performance in patients with Parkinson’s disease (PD)…Epigenome-wide meta-analysis of sex-differential DNA methylation in Parkinson’s disease
Objective: To comprehensively characterize the blood-based DNA methylation alterations related to sex in patients with Parkinson's disease (PD), shedding light on the underlying genes and…Cortical thickness and global atrophy progression in Parkinson’s disease with probable RBD
Objective: To explore 3-year cortical thickness (CTh) and global atrophy progression in treated Parkinson’s disease (PD) with probable REM sleep behavior disorder (RBD). Background: Parkinson’s…Lysosomal-driven reduction of alpha-synuclein aggregates in a neuron-like model of Parkinson’s disease
Objective: To test whether PIKfyve inhibition results in a lysosomal-driven reduction of alpha-synuclein aggregates in a mutant neuroblastoma cell line overexpressing an aggregation-prone form of…Preliminary Report on the efficacy of Allogeneic Bone marrow-derived Mesenchymal Stem Cells as a disease-modifying therapy for idiopathic Parkinson’s disease: Phase IIa double-blind, randomized controlled trial.
Objective: To select the safest and most effective number of repeat doses of allogeneic mesenchymal stem cells (MSC) delivered intravenously to slow the progression of…
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