Outcomes of Algorithm Guided DBS Programming: A case series
Objective: With the growing availability of technology-guided deep brain stimulation (DBS) programming, it is increasingly challenging to determine when and how to use these technologies…Altered Tryptophan Metabolism and the Role of the Kynurenine Pathway in Multiple System Atrophy
Objective: To elucidate cerebrospinal fluid (CSF) tryptophan metabolism in multiple system atrophy (MSA), focusing on alterations in the kynurenine pathway and its pathological implications. Background:…White Matter Abnormalities in Progressive Supranuclear Palsy (PSP) vs. Parkinson’s Disease (PD): Evaluation with a Convolutional Neural Network (CNN)-Based Tool
Objective: This study aimed to compare white matter hyperintensity (WMH) burden between PSP and PD using a novel AI-based tool for more accurate WMH volume…Quantitative Gait Evaluation in Multiple System Atrophy: Supervised versus Unsupervised Analysis
Objective: This study aims to compare gait parameters in real-world (RW) home settings with supervised clinical assessments on 6-minutes walking test (6MWT) in MSA patients…Carbidopa/levodopa related hypotension in patients with alpha-synucleinopathies
Objective: Evaluate blood pressure response to levodopa/carbidopa in patients with synucleinopathies undergone to autonomic testing. Background: Carbidopa/levodopa is the mainstay treatment of patients with synucleinopathies,…The importance of vascular anomalies and endothelin-1 factor in the development of vascular parkinsonism
Objective: To study the relationship between vascular endothelium and vascular anomalies in the development of vascular parkinsonism. Background: Although vascular parkinsonism (VP) is relatively rare,…Juvenile parkinsonism masquerading as hereditary spastic paraplegia
Objective: To present a patient with juvenile parkinsonism initially presented with billateral foot dystonia and inreased deep tendon reflexes. Background: Patients with juvenile parkinsonism may…Gait Analysis and Outcome of CSF Drainage in Patients of Normal Pressure Hydrocephalus
Objective: NPH is a clinical entity causing impairment in gait, bladder and memory functions. Of these, gait dysfunction is the most prominent and disabling as…Topographical heterogeneity of cholinergic system status in Multiple System Atrophy: A series report
Objective: To characterize individual-level topographical patterns of cholinergic upregulation and downregulation in Multiple System Atrophy (MSA) using a whole brain voxel-wise approach. Background: MSA is…Concomitant Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis Versus Motoneuron Phenotype of PSP in Ukrainian Patient
Objective: To provide a description of a rare case of mixed progressive supranuclear palsy (PSP) and amyotrophic lateral sclerosis (ALS) in Ukrainian patient. Background: The…
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