Therapeutic Efficacy of a Next-Generation 16-Contact Directional Deep Brain Stimulation System in Parkinson’s Disease
Objective: We assessed the clinical efficacy and safety of a novel deep brain stimulation (DBS) system equipped with 16-contact directional leads in improving motor symptoms…Video-Based Gait Analysis for Objective Assessment of Motor Severity and Surgical Outcome in Parkinson’s Disease: A Scalable Alternative to Subjective Rating
Objective: To evaluate the accuracy of a gait-focused video analysis model in predicting clinical scores and post-surgical improvement in Parkinson’s disease (PD) Background: The MDS-UPDRS…Efficacy and Adverse Events of Tetrabenazine, Deutetrabenazine, and Valbenazine in Huntington’s Disease
Objective: To compare the efficacy and safety of tetrabenazine, deutetrabenazine, and valbenazine for chorea and neuropsychiatric outcomes in Huntington’s disease (HD). Background: Vesicular monoamine transporter…Transcutaneous Spinal Cord Stimulation in Hereditary Spastic Paraplegias
Objective: To assess transcutaneous spinal cord stimulation (tSCS) as a treatment for hereditary spastic paraplegias (HSPs). Background: Hereditary spastic paraplegias (HSPs) are genetic disorders characterized…Integrating Transcriptomics and Morphological Profiling to Characterize GBA-Associated Parkinson’s Disease in Midbrain Organoids
Objective: This study characterizes converging biological trends in GBA-associated Parkinson’s Disease by integrating transcriptomic profiling with exploratory image-based analysis of donor-matched midbrain organoids. Background: High-content…Non-Motor Symptom Improvement as a Driver of Quality of Life after Subthalamic Stimulation in Symmetric Parkinson’s Disease
Objective: To investigate non-motor outcomes in patients with symmetric vs. asymmetric motor symptoms following subthalamic stimulation (STN-DBS) in Parkinson’s disease (PD). Background: Motor asymmetry is…The Impact of Demographic Factors on Skull Density Ratios in a Hawaii Cohort
Objective: To understand the impact of demographic factors on skull density ratio (SDR) in Hawai‘i patients. Background: SDR is a validated indicator of the ability…When Muscles Relax but Symptoms Persist: A Case of Dysfunctional Sensory-Motor Cortical Integration in Botulinum Toxin-Resistant Blepharospasm
Objective: To present a case of blepharospasm (BSP) with objective response to serial botulinum toxin injections but persistent subjective symptoms, highlighting the role of sensory…Underestimation of Nighttime Sleep Symptoms in Isolated RBD is Associated with Increased Risk of Phenoconversion to Synucleinopathy: A North American Prodromal Synucleinopathy Consortium Study
Objective: To determine whether mismatch between participant (PT) self-perceived and bed partner (BP)–reported sleep symptoms is associated with risk of phenoconversion to synucleinopathy. Background: Patients…Regional Homogeneity in the Visual Network Mediates between Microbiota and Cognition in Parkinson’s Disease
Objective: We study the role of spontaneous brain activity in the cross-talk between gut microbiota and cognition in PD. Background: Gut dysbiosis is a prevalent…
- « Previous Page
- 1
- …
- 50
- 51
- 52
- 53
- 54
- …
- 1942
- Next Page »