Priorities of PD patients for treatment of cognitive-driven ADL impairment
Objective: To define cognitive-driven impairments in activities of daily living (ADL) with high priority for rehabilitation ranked by Parkinson’s disease (PD) patients. Background: Impairments in…Motor decision-making in Parkinson’s disease
Objective: The aim of this study is to test motor decision-making ability in Parkinson's disease (PD) in conditions with different biomechanical properties and levels of…The position of students of communication sciences and disorders department at Ono Academic College regarding telepractice vs. face-to-face internship experience in speech and swallowing therapy for patients with movement disorders.
Objective: To assess the position of students from the communication sciences and disorders department (CSD) regarding telepractice vs. face-to-face internship in speech and swallowing therapy…Long-term safety of continuous levodopa/carbidopa infusion with ND0612: Data from patients who continued past one year in the BeyoND study
Objective: To report long-term safety and tolerability data from the ongoing BeyoND study (NCT02726386) for patients who continued treatment past the one-year primary endpoint. Background:…Plasma p-Tau181 and p-Tau231 in Parkinson’s Disease
Objective: To explore whether plasma phosphorylated tau (p-Tau) 181 and p-Tau231 levels are associated with cognition in a Parkinson’s Disease (PD) cohort. Background: We recently…Classical Machine Learning approaches to automate tremor detection from electrophysiological data
Objective: To detect tremor syndromes from electrophysiological signatures using classical machine learning techniques. Background: Electromyographic recordings combined with accelerometry data are widely used to measure…A facilitated self-management toolkit for people with Parkinson’s disease: A feasibility study of ‘Live Well with Parkinson’s
Objective: To assess the feasibility and acceptability of a theory and evidence-based digital facilitated self-management toolkit for people with Parkinson’s: ‘Live Well with Parkinson’s’. Background:…Inflammatory microglial and astroglial phenotype associated with pathological alpha-synuclein inclusions in the substantia nigra
Objective: To characterize neuroinflammatory gene expression in microglia and astrocytes associated with early alpha-synuclein (a-syn) inclusion formation. Background: Parkinson’s disease (PD) is characterized by alpha-synuclein…Isolated craniocervical dystonia without neuropsychiatric manifestations associated with NMDA-receptor antibodies
Objective: N-methyl-D-aspartate receptor (NMDAR) encephalitis classically spans neuropsychiatric disturbance, autonomic dysfunction and salient movement disorders. Attenuated presentations are increasingly recognised; however, presentations with an isolated…Alterations in neuron-derived exosomal cargo in Parkinson Disease
Objective: The main objectives are 1) the confirmation of exosome isolation, based on iPSC-derived midbrain neuron model, 2) the identification of α-synuclein cargo of PD-patient…
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