Feasibility of video-based motion analysis to rate the severity of tremor and bradykinesia in Parkinson’s disease
Objective: To evaluate the feasibility of video-based motion analysis for rating resting tremor and finger tapping in Parkinson’s disease. Background: Unified Parkinson’s Disease Rating Scale…Endorsement of self-reported non-motor symptoms is associated with higher self-rated motor experiences of daily living in MDS-UPDRS part 2 in Parkinson’s disease
Objective: To quantify the extent to which self-perceived motor limitations (MDS-UPDRS part 2) relate to self-reported levels of non-motor symptom severity. Background: The MDS-UPDRS part…Item Response Theory Analysis of the MDS-UPDRS Motor Examination: Tremor vs. Non-tremor Items
Objective: To investigate the dimensionality of MDS-UPRS Motor Examination (Part 3) using Item Response Theory (IRT). Background: In Parkinson's disease (PD), tremor severity behaves differently…Development and Validation of the Orthostatic Tremor Severity and Disability Scale (OT-10)
Objective: To develop and validate a severity and disability self-administered scale for orthostatic tremor (OT). Background: OT is characterized by a 13-18 Hz tremor in…Developing A Novel Disease-Specific Psychosis Severity Scale in Parkinson’s disease (Psy-PD): A Pilot Study
Objective: To develop and assess the psychometrics of a disease-specific psychosis severity rating scale (Psy-PD) for a one-stop assessment of change in psychotic symptoms in…Lack of sensitivity of full-depth upper gastrointestinal specimens as a prodromal biomarker for synucleinopathy in idiopathic REM sleep behavior disorder
Objective: To examine the phosphorylated alpha-synuclein (pAS) immunohistochemistry of the upper gastrointestinal (GI) tract tissue as a “prodromal” pathologic biomarker for synucleinopathy in idiopathic rapid…Longitudinal change in dopamine transporter availability in idiopathic REM sleep behavior disorder
Objective: To elucidate longitudinal changes in the dopamine transporter (DAT) availability in idiopathic rapid-eye-movement sleep behavior disorder (iRBD) patients predicted by the baseline motor and…SNCA hypomethylation in rapid eye movement sleep behavior disorder is a potential biomarker for Parkinson’s disease
Objective: We aimed to explore whether there were different distributions of α-synuclein at a genetic and/or protein level in patients with iRBD. Background: α-Synuclein has been related to…Shear wave sonoelastography is effective in detecting myofascial trigger points and spasticity
Objective: The aim was to evaluate effectiveness of shear wave sonoelastography is effective in detecting myofascial trigger points (MTrP) and spasticity. Background: Ultrasound (US) revolutionized…Perceptions of burden of spasticity and treatment satisfaction among post-stroke patients over the course of a botulinum neurotoxin A (BoNT-A) treatment cycle: An ethnographic study
Objective: To design an ethnographic study following patients over a botulinum toxin type-A (BoNT-A) treatment cycle to inform individualized treatment. Background: The concept of individualized…
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