Real-world database analysis of new-onset hypotension and medications for orthostatic hypotension prescribing patterns in patients with Parkinson’s Disease receiving MAO-B Inhibitors and levodopa in Japan
Objective: To evaluate the incidence of claims-defined new-onset hypotension and the prescribing patterns of medications for orthostatic hypotension in patients with Parkinson’s disease (PD) treated…Suicidal Ideation and the Hippocampal Histaminergic System in Huntington’s Disease: A PET Study
Objective: To determine whether presence and severity of suicidal ideation (SI) are associated with hippocampal volume and histamine H3 receptor (H3R) PET uptake in people with Huntington’s disease (PwHD). Background: Suicidal ideation occurs in approximately 8–27% of PwHD, yet its causes remain unclear(1–3). The…Integrated and Multidisciplinary Care for Older Adults with Parkinson’s Disease: A value-driven approach
Objective: To evaluate value driven outcomes of an integrated multidisciplinary Parkinson’s clinic for older adults in Singapore Background: Parkinson’s Disease (PD) is a complex neurodegenerative…Comparative efficacy and safety of Safinamide versus Opicapone in Japanese patients with Parkinson’s Disease and wearing-off: A matching-adjusted indirect comparison
Objective: To compare efficacy and safety outcomes with safinamide and opicapone as adjuncts to levodopa in Parkinson’s disease (PD) patients with wearing-off using an anchored…Real-World Mobile Voice Classification for Parkinson’s Disease Using Convolutional Neural Networks and Mel-Spectrogram Features
Objective: To evaluate the performance of deep learning approach based on Mel-spectrogram features in classifying PD using two real-world speech tasks - sustained phonation and…Association of Glymphatic Flow at Diffusion Tensor Image with Motor Symptoms and Striatal Dopamine Degeneration in Parkinson’s Disease
Objective: This study aimed to investigate the association between the diffusion tensor image (DTI) analysis along the perivascular space (ALPS) index, dopamine transporter (DAT) availability…Early Clinical Characteristics of Pathologically Confirmed Progressive Supranuclear Palsy and Corticobasal Degeneration
Objective: This study aimed to characterize the early clinical features of PSP and CBD to inform clinicians on diagnostic assessment and management strategies. Background: Although…Qihuang Needle Therapy for Motor Symptoms in Parkinson’s Disease: A Randomized Controlled Trial
Objective: To evaluate the efficacy of Qihuang needle therapy for improving motor and non-motor symptoms in patients with Parkinson’s disease (PD). Background: Motor symptoms in…Risk factors for dysautonomic fluctuations in Mexican PwP
Objective: To identify risk factors for non-motor dysautonomic fluctuations in people living with Parkinson’s disease (PwP). Background: Advanced Parkinson’s disease (PD) is characterized by motor…Digital Health, Telemedicine, and Artificial Intelligence in Parkinson’s Disease Management During COVID-19: A Narrative Review
Objective: The objective of this narrative review was to evaluate the effectiveness of telemedicine and AI-based technologies used for the remote monitoring and management of…
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