A phase 2b randomized, double-blind, placebo-controlled study of suvecaltamide in the treatment of adults with moderate to severe essential tremor: study design and methodology
Objective: Evaluate the efficacy and safety of JZP385 (formerly CX-8998), a highly selective T-type calcium channel modulator, for symptomatic control of moderate to severe essential…Tremor after organ transplantation: prevalence and characteristics
Objective: Here we report on the largest population of solid organ transplant recipients that was investigated with clinical neurophysiological methods, to objectively establish the tremor…Cerebellar Pathway Outflow Tremor from Thalamic and Midbrain Glioma Responded to Dopaminergic Therapy
Objective: To describe a case of cerebellar pathway outflow tremor caused by denervation of the dopaminergic pathway from thalamic and midbrain glioma, which responded to…Regional free-water differentially associated with glial activation, neuroinflammation, and neurodegeneration in de novo Parkinson’s disease
Objective: Assess to what extent free-water(FW) as measured by diffusion-weighted MRI(dMRI) is a neuroimaging marker of glial activation, neuroinflammation, and neurodegeneration in de novo Parkinson’s disease(PD) patients from…Brain atrophy progression in de novo Parkinson’s disease
Objective: Using deformation-based morphometry (DBM) as a measure of atrophy, the aim of this study was to identify the regions presenting structural brain changes after…Neuroimaging Extra-Striatal D2 Receptors in Parkinson’s Disease with Rapid Eye Movement Sleep Behaviour Disorder
Objective: Our aim was to characterize the extra-striatal dopamine in Parkinson’s disease (PD) with and without rapid eye movement sleep behaviour disorder (RBD) using in…Prefrontal cortical activity and the control of walking in people with freezing of gait
Objective: To investigate the influence of freezing of gait (FoG) on automaticity of walking in people with Parkinson’s disease (PD). Background: A hallmark of healthy…Progression of cortical thinning in Parkinson’s disease
Objective: We sought to validate cortical thickness as an objective biomarker of Parkinson’s disease (PD) progression. Background: Cortical thickness analysis has been proposed as a…Decreased Availability of Adenosine 2A Receptors in the Caudate in Patients with Early Stage Parkinson’s Disease
Objective: The aim of this study was to investigate Adenosine 2A (A2A) receptor availability in patients with early and moderate stage Parkinson’s disease (PD). Background:…Normative vs. patient-specific brain connectivity in Deep Brain Stimulation
Objective: The objective of this study was to compare similarities and differences between patient-specific, disease-matched and normative structural connectivity seeding from deep brain stimulation (DBS)…
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